Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis
Laparoscopic distal pancreatectomy is a minimally invasive approach for the surgical treatment of neoplasms in the distal pancreas. This study aimed to compare this approach to the open procedure. A retrospective analysis of a prospectively maintained database of 400 pancreatectomies was performed....
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2025-01-01
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| author | Irena Plahuta Žan Šarenac Medeja Golob Špela Turk Bojan Ilijevec Tomislav Magdalenić Stojan Potrč Arpad Ivanecz |
| author_facet | Irena Plahuta Žan Šarenac Medeja Golob Špela Turk Bojan Ilijevec Tomislav Magdalenić Stojan Potrč Arpad Ivanecz |
| author_sort | Irena Plahuta |
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| description | Laparoscopic distal pancreatectomy is a minimally invasive approach for the surgical treatment of neoplasms in the distal pancreas. This study aimed to compare this approach to the open procedure. A retrospective analysis of a prospectively maintained database of 400 pancreatectomies was performed. The laparoscopic distal pancreatectomy group (LDP) was compared to the open distal pancreatectomy group (ODP). A propensity score matching analysis (PSM) was performed. From 2016 to 2023, 108 distal pancreatectomies were carried out, 19 (17.6%) laparoscopically and 89 (82.4%) openly. The conversion rate was 13.6%. The severe morbidity rates were 28.1% in the ODP group, 47.4% in the LDP group, and 15.8% in the ODP-PSM group. The difference between the latter two was statistically significant (<i>p</i> = 0.034) due to the high rate of Clavien–Dindo grade 3a complications (42.1% versus 10.5%, <i>p</i> = 0.042) in the LDP group. The 90-day mortality rates were 3.3% in the ODP group and 5.3% in the other two groups. The LDP group had a shorter duration of intravenous narcotic analgesia (5 versus 7 days, <i>p</i> = 0.041). There was no difference in the R0 resection or postoperative pancreatic fistula rates. Our attention should be drawn to preventing postoperative complications because the oncological outcomes are already comparable with those of the open procedure, and postoperative pain management is promising. |
| format | Article |
| id | doaj-art-72089906ea654e69b0389cc6919dd35a |
| institution | Kabale University |
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| publishDate | 2025-01-01 |
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| series | Life |
| spelling | doaj-art-72089906ea654e69b0389cc6919dd35a2025-01-24T13:38:46ZengMDPI AGLife2075-17292025-01-011519710.3390/life15010097Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching AnalysisIrena Plahuta0Žan Šarenac1Medeja Golob2Špela Turk3Bojan Ilijevec4Tomislav Magdalenić5Stojan Potrč6Arpad Ivanecz7Clinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaDepartment of Surgery, Faculty of Medicine, University of Maribor, Taborska Ulica 8, 2000 Maribor, SloveniaDepartment of Surgery, Faculty of Medicine, University of Maribor, Taborska Ulica 8, 2000 Maribor, SloveniaClinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaClinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaClinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaClinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaClinical Department of Abdominal and General Surgery, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, SloveniaLaparoscopic distal pancreatectomy is a minimally invasive approach for the surgical treatment of neoplasms in the distal pancreas. This study aimed to compare this approach to the open procedure. A retrospective analysis of a prospectively maintained database of 400 pancreatectomies was performed. The laparoscopic distal pancreatectomy group (LDP) was compared to the open distal pancreatectomy group (ODP). A propensity score matching analysis (PSM) was performed. From 2016 to 2023, 108 distal pancreatectomies were carried out, 19 (17.6%) laparoscopically and 89 (82.4%) openly. The conversion rate was 13.6%. The severe morbidity rates were 28.1% in the ODP group, 47.4% in the LDP group, and 15.8% in the ODP-PSM group. The difference between the latter two was statistically significant (<i>p</i> = 0.034) due to the high rate of Clavien–Dindo grade 3a complications (42.1% versus 10.5%, <i>p</i> = 0.042) in the LDP group. The 90-day mortality rates were 3.3% in the ODP group and 5.3% in the other two groups. The LDP group had a shorter duration of intravenous narcotic analgesia (5 versus 7 days, <i>p</i> = 0.041). There was no difference in the R0 resection or postoperative pancreatic fistula rates. Our attention should be drawn to preventing postoperative complications because the oncological outcomes are already comparable with those of the open procedure, and postoperative pain management is promising.https://www.mdpi.com/2075-1729/15/1/97laparoscopic distal pancreatectomysplenectomypostoperative pancreatic fistulaintravenous narcotic analgesiamorbiditymortality |
| spellingShingle | Irena Plahuta Žan Šarenac Medeja Golob Špela Turk Bojan Ilijevec Tomislav Magdalenić Stojan Potrč Arpad Ivanecz Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis Life laparoscopic distal pancreatectomy splenectomy postoperative pancreatic fistula intravenous narcotic analgesia morbidity mortality |
| title | Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis |
| title_full | Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis |
| title_fullStr | Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis |
| title_full_unstemmed | Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis |
| title_short | Laparoscopic and Open Distal Pancreatectomy—An Initial Single-Institution Experience with a Propensity Score Matching Analysis |
| title_sort | laparoscopic and open distal pancreatectomy an initial single institution experience with a propensity score matching analysis |
| topic | laparoscopic distal pancreatectomy splenectomy postoperative pancreatic fistula intravenous narcotic analgesia morbidity mortality |
| url | https://www.mdpi.com/2075-1729/15/1/97 |
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