Integrated single-cell transcriptome and TCR profiles of hepatocellular carcinoma highlight the convergence on interferon signaling during immunotherapy

Integrated single-cell transcriptome and TCR profiles of hepatocellular carcinoma highlight the convergence on interferon signaling during immunotherapy

Background Despite the success of immune checkpoint inhibitor (ICI)-based combination therapies in hepatocellular carcinoma (HCC), its effectiveness remains confined to a subset of patients. The development of reliable, predictive markers is important for accurate patient stratification and further...

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Main Authors: Xiaobo Li, Chang Xu, Mingjie Zhang, Shengnan Guo, Dapeng Hao, Changqing Liu, Jing Ren, Guangyu Wang, Cheng Lyu, Tianhao Li, Huanhuan Xu, Zepeng Hou, Mingshuo Zhang, Dan Kong
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/11/e010534.full
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