A case report of hermaphrodite goat: clinical and genetic approach
This case report describes clinical examination and cytogenetic and molecular genetic analyses of a hermaphrodite mixed Maltese breed goat that was referred to the Gynecology Clinic of the Faculty of Veterinary Medicine, Selcuk University in 2010. In anamnesis, goat was a single kid at the birth and...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1054 |
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| author | Çağlayan Özel Gonca Şen Mustafa Hitit Nadir Koçak Aydın Güzeloğlu Ahmet Semacan Ercan Kurar Ercan |
| author_facet | Çağlayan Özel Gonca Şen Mustafa Hitit Nadir Koçak Aydın Güzeloğlu Ahmet Semacan Ercan Kurar Ercan |
| author_sort | Çağlayan Özel |
| collection | DOAJ |
| description | This case report describes clinical examination and cytogenetic
and molecular genetic analyses of a hermaphrodite
mixed Maltese breed goat that was referred to the Gynecology
Clinic of the Faculty of Veterinary Medicine, Selcuk University
in 2010. In anamnesis, goat was a single kid at the birth
and was polled. Clitoris was 1.9x0.9 cm in size and vagina
was shorter than normal. By palpation and ultrasonographic
examination, it was determined that the right (4.88 cm) and
left (2.87 cm) testicles were located under skin in the inguinal
region. Breast and nipples were in normal size. There
was a rudimentary penis located under skin but no scrotum
or prepitium was observed. After chromosome preparation
using peripheral blood samples and GTG staining, appropriate
metaphases were analyzed using an image analyzer program.
Genomic DNA was isolated from the blood sample. Sexdetermining
region Y (SRY) and amelogenin gene regions
were amplified using polymerase chain reaction (PCR) including
positive and negative controls. In karyotype analysis,
metaphase plaque was observed as 60,XY. In PCR analysis, no
SRY amplification was determined and only AMX allele was
observed for amelogenin locus. Hermaphroditism is widely
observed in goats and a number different mechanisms were
reported. It is suggested that polled rams should be culled
and karyotype and molecular genetics analyses should be
performed to evaluate hermaphrodite cases in detail. |
| format | Article |
| id | doaj-art-71f905ed039d40dfa8ae4ceadfda3314 |
| institution | DOAJ |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-71f905ed039d40dfa8ae4ceadfda33142025-08-20T02:52:06ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19533042272311054A case report of hermaphrodite goat: clinical and genetic approachÇağlayan Özel01Gonca Şen2Mustafa Hitit3Nadir Koçak4Aydın Güzeloğlu5Ahmet Semacan6Ercan Kurar7Ercan8Selçuk Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Konya, TürkiyeKırıkkale Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Kırıkkale, TürkiyeSelçuk Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Konya, TürkiyeSelçuk Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Konya, TürkiyeSelçuk Üniversitesi, Tıp Fakültesi, Tıbbi Genetik Anabilim Dalı, Konya, TürkiyeSelçuk Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Konya, Türkiye Selçuk Üniversitesi, Veteriner Fakültesi, Doğum ve Jinekoloji Anabilim Dalı, Konya, TürkiyeSelçuk Üniversitesi, Veteriner Fakültesi, Genetik Anabilim Dalı, Konya, TürkiyeNecmettin Erbakan Üniversitesi, Meram Tıp Fakültesi, Tıbbi Biyoloji Anabilim Dalı, Konya, TürkiyeThis case report describes clinical examination and cytogenetic and molecular genetic analyses of a hermaphrodite mixed Maltese breed goat that was referred to the Gynecology Clinic of the Faculty of Veterinary Medicine, Selcuk University in 2010. In anamnesis, goat was a single kid at the birth and was polled. Clitoris was 1.9x0.9 cm in size and vagina was shorter than normal. By palpation and ultrasonographic examination, it was determined that the right (4.88 cm) and left (2.87 cm) testicles were located under skin in the inguinal region. Breast and nipples were in normal size. There was a rudimentary penis located under skin but no scrotum or prepitium was observed. After chromosome preparation using peripheral blood samples and GTG staining, appropriate metaphases were analyzed using an image analyzer program. Genomic DNA was isolated from the blood sample. Sexdetermining region Y (SRY) and amelogenin gene regions were amplified using polymerase chain reaction (PCR) including positive and negative controls. In karyotype analysis, metaphase plaque was observed as 60,XY. In PCR analysis, no SRY amplification was determined and only AMX allele was observed for amelogenin locus. Hermaphroditism is widely observed in goats and a number different mechanisms were reported. It is suggested that polled rams should be culled and karyotype and molecular genetics analyses should be performed to evaluate hermaphrodite cases in detail.http://eurasianjvetsci.org/pdf.php3?id=1054goathermaphroditismkaryotypesryamelogenin |
| spellingShingle | Çağlayan Özel Gonca Şen Mustafa Hitit Nadir Koçak Aydın Güzeloğlu Ahmet Semacan Ercan Kurar Ercan A case report of hermaphrodite goat: clinical and genetic approach Eurasian Journal of Veterinary Sciences goat hermaphroditism karyotype sry amelogenin |
| title | A case report of hermaphrodite goat: clinical and genetic approach |
| title_full | A case report of hermaphrodite goat: clinical and genetic approach |
| title_fullStr | A case report of hermaphrodite goat: clinical and genetic approach |
| title_full_unstemmed | A case report of hermaphrodite goat: clinical and genetic approach |
| title_short | A case report of hermaphrodite goat: clinical and genetic approach |
| title_sort | case report of hermaphrodite goat clinical and genetic approach |
| topic | goat hermaphroditism karyotype sry amelogenin |
| url | http://eurasianjvetsci.org/pdf.php3?id=1054 |
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