The UCP2/PINK1/LC3b-mediated mitophagy is involved in the protection of NRG1 against myocardial ischemia/reperfusion injury

The UCP2/PINK1/LC3b-mediated mitophagy is involved in the protection of NRG1 against myocardial ischemia/reperfusion injury

Available evidence indicates that neuregulin-1 (NRG-1) can provide a protection against myocardial ischemia/reperfusion (I/R) injury and is involved in various cardioprotective interventions by potential regulation of mitophagy. However, the molecular mechanisms linking NRG-1 and mitophagy remain to...

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Bibliographic Details
Main Authors: Xin-Tao Li, Xin-Yue Li, Tian Tian, Wen-He Yang, Shuai-Guo Lyv, Yi Cheng, Kai Su, Xi-Hua Lu, Mu Jin, Fu-Shan Xue
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Redox Biology
Subjects:
Ischemia/reperfusion injury
Neuregulin-1
Mitophagy
Uncoupling protein 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000242
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