Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree‐Based Dimensionality Reduction

Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree‐Based Dimensionality Reduction

Background Abnormal ventricular depolarization, evident as a broad QRS complex on an ECG, is traditionally categorized into left bundle‐branch block (LBBB) and right bundle‐branch block or nonspecific intraventricular conduction delay. This categorization, although physiologically accurate, may fail...

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Main Authors: Mehak Gurnani, Konstantinos Patlatzoglou, Joseph Barker, Derek Bivona, Libor Pastika, Ewa Sieliwonczyk, Boroumand Zeidaabadi, Paolo Inglese, Lara Curran, Ahran D. Arnold, Declan O'Regan, Zachary Whinnett, Kenneth C. Bilchick, Nicholas S. Peters, Daniel B. Kramer, Jonathan W. Waks, Arunashis Sau, Fu Siong Ng
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
bundle‐branch block
clustering
ECG
machine learning
phenotyping
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040814
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