Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma.
Asthma is a common allergic lung disease frequently affecting individuals with a prior history of eczema/atopic dermatitis (AD); however, the mechanism underlying the progression from AD to asthma (the so-called "atopic march") is unclear. Here we show that, like humans with AD, mice with...
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| Main Authors: | Shadmehr Demehri, Mitsuru Morimoto, Michael J Holtzman, Raphael Kopan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-05-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000067&type=printable |
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