A COMPARATIVE STUDY OF DRUG RELEASE FROM POLYCOMPLEX MATRICES IN STANDARD AND BIORELEVANT MEDIA USING USP III AND USP IV APPARATUS

A COMPARATIVE STUDY OF DRUG RELEASE FROM POLYCOMPLEX MATRICES IN STANDARD AND BIORELEVANT MEDIA USING USP III AND USP IV APPARATUS

The results of Indomethacin release from the oral drug delivery systems based on interpolymer complexes with Eudragit® copolymers are presented. The release assessment was performed by two methods - flow-through cell (USP IV Apparatus) and the reciprocating cylinder (USP III Apparatus) in standard b...

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Bibliographic Details
Main Authors: A. V. Sitenkova (Bukhovets), N. Fotaki, R. I. Moustafine
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
dissolution test
biorelevant media
indomethacin
interpolymer complexes
oral drug delivery systems
eudragit®
Online Access:https://www.pharmjournal.ru/jour/article/view/333
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