Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review
Circumcision is one of the most commonly performed operations. It is common to use of antibiotics to prevent complications after circumcision. However, as awareness of antibiotic resistance increases, it is necessary to consider using other prophylactic drugs. This review aims to evaluate non-antibi...
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| Language: | English |
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Medical University of Gdańsk
2024-06-01
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| Series: | European Journal of Translational and Clinical Medicine |
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| Online Access: | https://ejtcm.gumed.edu.pl/articles/189242.pdf |
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| author | Ulinnuha Khirza Kafalah Muhammad Luthfi Adnan |
| author_facet | Ulinnuha Khirza Kafalah Muhammad Luthfi Adnan |
| author_sort | Ulinnuha Khirza Kafalah |
| collection | DOAJ |
| description | Circumcision is one of the most commonly performed operations. It is common to use of antibiotics to prevent complications after circumcision. However, as awareness of antibiotic resistance increases, it is necessary to consider using other prophylactic drugs. This review aims to evaluate non-antibiotic drugs for wound healing after circumcision. We conducted a literature search in accordance with the PRISMA guidelines using Google Scholar, PubMed, and ScienceDirect search engines to find treatment intervention studies comparing circumcision wound healing outcomes and adverse effects after non-antibiotic topical drugs and antibiotics. A total of 2 studies with 636 participants matched our inclusion criteria. 2-octyl cyanoacrylate and nanosilver gel (AgNPs) were used for post-circumcision wound treatment. The group with topical non-antibiotic drugs had a lower healing rate. There was no significant difference between wound healing and significant adverse effects between drug comparisons. Antibiotic resistance tests between intervention and control groups were not included in these studies. Data comparing non-antibiotic drugs and antibiotics for post-circumcision wound healing are still limited. Further studies conducted in various settings are needed to assess the efficacy of non-antibiotic topical agents for post-circumcision wound healing and reducing antibiotic resistance. |
| format | Article |
| id | doaj-art-71b22e9f35644eae82e36b3a75269c72 |
| institution | DOAJ |
| issn | 2657-3148 2657-3156 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Medical University of Gdańsk |
| record_format | Article |
| series | European Journal of Translational and Clinical Medicine |
| spelling | doaj-art-71b22e9f35644eae82e36b3a75269c722025-08-20T03:01:30ZengMedical University of GdańskEuropean Journal of Translational and Clinical Medicine2657-31482657-31562024-06-01717986189242Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic reviewUlinnuha Khirza Kafalah0https://orcid.org/0009-0003-6403-8569Muhammad Luthfi Adnan1https://orcid.org/0000-0003-0733-1948Emergency Department, Regional General Hospital Prambanan, Yogyakarta, IndonesiaDepartment of Physiology, Faculty of Medicine, Universitas Islam, Yogyakarta, IndonesiaCircumcision is one of the most commonly performed operations. It is common to use of antibiotics to prevent complications after circumcision. However, as awareness of antibiotic resistance increases, it is necessary to consider using other prophylactic drugs. This review aims to evaluate non-antibiotic drugs for wound healing after circumcision. We conducted a literature search in accordance with the PRISMA guidelines using Google Scholar, PubMed, and ScienceDirect search engines to find treatment intervention studies comparing circumcision wound healing outcomes and adverse effects after non-antibiotic topical drugs and antibiotics. A total of 2 studies with 636 participants matched our inclusion criteria. 2-octyl cyanoacrylate and nanosilver gel (AgNPs) were used for post-circumcision wound treatment. The group with topical non-antibiotic drugs had a lower healing rate. There was no significant difference between wound healing and significant adverse effects between drug comparisons. Antibiotic resistance tests between intervention and control groups were not included in these studies. Data comparing non-antibiotic drugs and antibiotics for post-circumcision wound healing are still limited. Further studies conducted in various settings are needed to assess the efficacy of non-antibiotic topical agents for post-circumcision wound healing and reducing antibiotic resistance.https://ejtcm.gumed.edu.pl/articles/189242.pdfantimicrobial resistanceantibioticcircumcisionpostoperative managementtopical agents |
| spellingShingle | Ulinnuha Khirza Kafalah Muhammad Luthfi Adnan Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review European Journal of Translational and Clinical Medicine antimicrobial resistance antibiotic circumcision postoperative management topical agents |
| title | Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review |
| title_full | Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review |
| title_fullStr | Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review |
| title_full_unstemmed | Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review |
| title_short | Comparison of the use of non-antibiotic drugs with antibiotics in postoperative circumcision wound healing: a systematic review |
| title_sort | comparison of the use of non antibiotic drugs with antibiotics in postoperative circumcision wound healing a systematic review |
| topic | antimicrobial resistance antibiotic circumcision postoperative management topical agents |
| url | https://ejtcm.gumed.edu.pl/articles/189242.pdf |
| work_keys_str_mv | AT ulinnuhakhirzakafalah comparisonoftheuseofnonantibioticdrugswithantibioticsinpostoperativecircumcisionwoundhealingasystematicreview AT muhammadluthfiadnan comparisonoftheuseofnonantibioticdrugswithantibioticsinpostoperativecircumcisionwoundhealingasystematicreview |