Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer

Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer

Background Preoperative identification of breast cancer (BC) subtypes is essential for optimizing treatment strategies and improving patient outcomes. This study aimed to identify circulating cell-free DNA (cfDNA) methylation signatures to differentiate triple-negative breast cancer (TNBC) from othe...

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Bibliographic Details
Main Authors: Lijing Gao, Yanbing Li, Chao Qu, Yan Dong, Qingzhen Fu, Haibo Zhou, Ning Zhao, Xianyu Zhang, Da Pang, Yashuang Zhao
Format: Article
Language:English
Published: PeerJ Inc. 2025-08-01
Series:PeerJ
Subjects:
Triple-negative breast cancer
Cell-free DNA
Multiplex droplet digital PCR
DNA methylation
Differential diagnosis
Prognosis
Online Access:https://peerj.com/articles/19888.pdf
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