In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease

Saved in:
Bibliographic Details
Main Authors: Michal Geva, Ralf Reilmann, Robin Schubert, Kelly Chen, Y Paul Goldberg, Michael R. Hayden
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neurotherapeutics
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747925001540
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849765812333707264
author Michal Geva
Ralf Reilmann
Robin Schubert
Kelly Chen
Y Paul Goldberg
Michael R. Hayden
author_facet Michal Geva
Ralf Reilmann
Robin Schubert
Kelly Chen
Y Paul Goldberg
Michael R. Hayden
author_sort Michal Geva
collection DOAJ
format Article
id doaj-art-71aed8b677ab43b1a0e48db3c0153f77
institution DOAJ
issn 1878-7479
language English
publishDate 2025-07-01
publisher Elsevier
record_format Article
series Neurotherapeutics
spelling doaj-art-71aed8b677ab43b1a0e48db3c0153f772025-08-20T03:04:45ZengElsevierNeurotherapeutics1878-74792025-07-01224e0067610.1016/j.neurot.2025.e00676In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington diseaseMichal Geva0Ralf Reilmann1Robin Schubert2Kelly Chen3Y Paul Goldberg4Michael R. Hayden5Prilenia Therapeutics B.V.George Huntington InstituteGeorge Huntington InstitutePrilenia Therapeutics B.V.Prilenia Therapeutics B.V.Prilenia Therapeutics B.V.http://www.sciencedirect.com/science/article/pii/S1878747925001540
spellingShingle Michal Geva
Ralf Reilmann
Robin Schubert
Kelly Chen
Y Paul Goldberg
Michael R. Hayden
In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
Neurotherapeutics
title In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
title_full In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
title_fullStr In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
title_full_unstemmed In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
title_short In the phase 3 PROOF-HD trial, pridopidine shows consistent motor function improvements in Q-Motor measures, supporting Q-Motor as a predictive measure of long-term functional benefit and slower progression (cUHDRS) in Huntington disease
title_sort in the phase 3 proof hd trial pridopidine shows consistent motor function improvements in q motor measures supporting q motor as a predictive measure of long term functional benefit and slower progression cuhdrs in huntington disease
url http://www.sciencedirect.com/science/article/pii/S1878747925001540
work_keys_str_mv AT michalgeva inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease
AT ralfreilmann inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease
AT robinschubert inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease
AT kellychen inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease
AT ypaulgoldberg inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease
AT michaelrhayden inthephase3proofhdtrialpridopidineshowsconsistentmotorfunctionimprovementsinqmotormeasuressupportingqmotorasapredictivemeasureoflongtermfunctionalbenefitandslowerprogressioncuhdrsinhuntingtondisease