Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience
Background. The epidemiology of hospital-acquired infections (HAIs) has been less well studied in critically ill children in pediatric cardiothoracic intensive care units. This study aimed to investigate independent risk factors for and incidence of HAIs after cardiac surgery in children with...
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Hacettepe University Institute of Child Health
2023-10-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/87 |
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| author | Nimet Cındık Mahmut Gökdemir Mehmet Çelik Asım Çağrı Günaydın |
| author_facet | Nimet Cındık Mahmut Gökdemir Mehmet Çelik Asım Çağrı Günaydın |
| author_sort | Nimet Cındık |
| collection | DOAJ |
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Background. The epidemiology of hospital-acquired infections (HAIs) has been less well studied in critically ill children in pediatric cardiothoracic intensive care units. This study aimed to investigate independent risk factors for and incidence of HAIs after cardiac surgery in children with congenital heart disease (CHD).
Methods. Our study included 574 patients who underwent congenital heart surgery and were followed up in the cardiothoracic intensive care unit between September 2016 and December 2020. All patients were divided into four groups according to age: 0-1 months, 1-6 months, 6-12 months, and 1-18 years, and into two subgroups according to HAI development.
Results. The patients` median age and weight at surgery were 3.28 (interquartile range [IQR]): 0.43-8.1) months and 4.34 (IQR: 4.34-6.69) kg, respectively. HAIs and infection-related deaths were observed in 223 and 21 patients, respectively. Age at surgery, weight at surgery, concomitant syndromes and immunodeficiency status, presence of cyanotic heart disease, intubation, and use of antibiotics during hospitalization were statistically significant between the two groups with and without infection (p < 0.05). In logistic regression analysis, surgical weight < 5 kg (odds ratio [OR]: 2.55; 95% confidence interval [CI]: 1.56-4.17; p < 0.001), preoperative mechanical ventilation (OR: 2.0; 95% CI: 1.26-3.12; p=0.003), complexity of cardiac surgery according to the risk-adjusted congenital heart surgery classification score 3 (OR: 3.13; 95% CI: 1.24-7.92; p=0.016), presence of an concomitant syndrome (OR: 1.56; 95% CI: 1.02-2.88; p=0.040), age (OR: 1.01; 95% CI: 1.01-1.04; p=0.044) were independent risk factors for HAIs after cardiac surgery in children with CHD.
Conclusions. In this study, younger age, presence of an associated syndrome, preoperative mechanical ventilation, and weight less than 5 kg were found to be independent risk factors for HAI after cardiac surgery in children with CHD.
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| format | Article |
| id | doaj-art-71aaddcc5eaa4a5fa65d7eb745d02866 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-71aaddcc5eaa4a5fa65d7eb745d028662025-08-20T02:17:47ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212023-10-0165510.24953/turkjped.2022.169Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experienceNimet Cındık0Mahmut Gökdemir1Mehmet Çelik2Asım Çağrı Günaydın3Department of Pediatric Cardiology, Konya Practice and Research Center, Başkent University, Konya.Department of Pediatric Cardiology, Konya Practice and Research Center, Başkent University, Konya.Department of Cardiovascular Surgery, Konya Practice and Research Center, Başkent University, Konya, Türkiye.Department of Cardiovascular Surgery, Konya Practice and Research Center, Başkent University, Konya, Türkiye. Background. The epidemiology of hospital-acquired infections (HAIs) has been less well studied in critically ill children in pediatric cardiothoracic intensive care units. This study aimed to investigate independent risk factors for and incidence of HAIs after cardiac surgery in children with congenital heart disease (CHD). Methods. Our study included 574 patients who underwent congenital heart surgery and were followed up in the cardiothoracic intensive care unit between September 2016 and December 2020. All patients were divided into four groups according to age: 0-1 months, 1-6 months, 6-12 months, and 1-18 years, and into two subgroups according to HAI development. Results. The patients` median age and weight at surgery were 3.28 (interquartile range [IQR]): 0.43-8.1) months and 4.34 (IQR: 4.34-6.69) kg, respectively. HAIs and infection-related deaths were observed in 223 and 21 patients, respectively. Age at surgery, weight at surgery, concomitant syndromes and immunodeficiency status, presence of cyanotic heart disease, intubation, and use of antibiotics during hospitalization were statistically significant between the two groups with and without infection (p < 0.05). In logistic regression analysis, surgical weight < 5 kg (odds ratio [OR]: 2.55; 95% confidence interval [CI]: 1.56-4.17; p < 0.001), preoperative mechanical ventilation (OR: 2.0; 95% CI: 1.26-3.12; p=0.003), complexity of cardiac surgery according to the risk-adjusted congenital heart surgery classification score 3 (OR: 3.13; 95% CI: 1.24-7.92; p=0.016), presence of an concomitant syndrome (OR: 1.56; 95% CI: 1.02-2.88; p=0.040), age (OR: 1.01; 95% CI: 1.01-1.04; p=0.044) were independent risk factors for HAIs after cardiac surgery in children with CHD. Conclusions. In this study, younger age, presence of an associated syndrome, preoperative mechanical ventilation, and weight less than 5 kg were found to be independent risk factors for HAI after cardiac surgery in children with CHD. https://turkjpediatr.org/article/view/87congenital heart diseaseshospital-acquired infectionpediatric cardiac surgery |
| spellingShingle | Nimet Cındık Mahmut Gökdemir Mehmet Çelik Asım Çağrı Günaydın Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience The Turkish Journal of Pediatrics congenital heart diseases hospital-acquired infection pediatric cardiac surgery |
| title | Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience |
| title_full | Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience |
| title_fullStr | Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience |
| title_full_unstemmed | Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience |
| title_short | Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience |
| title_sort | risk factors for and incidence of hospital acquired infections after cardiac surgery in children with congenital heart disease a single center experience |
| topic | congenital heart diseases hospital-acquired infection pediatric cardiac surgery |
| url | https://turkjpediatr.org/article/view/87 |
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