Dynamics of T cell subpopulations and plasma cytokines during the first year of antineoplastic therapy in patients with breast cancer: the BEGYN-1 study

Dynamics of T cell subpopulations and plasma cytokines during the first year of antineoplastic therapy in patients with breast cancer: the BEGYN-1 study

Abstract Background The role of T cell immunity during antineoplastic therapy is poorly understood. In the BEGYN-1 study, patients with breast cancer underwent quarterly assessments prior to and during antineoplastic therapy over a period of 12 months. Methods We used flow cytometry and multiplex im...

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Bibliographic Details
Main Authors: Elisabeth Kaiser, Regine Weber, Melanie Hirschstein, Hala Mazid, Emilie Marie Suzanne Kapps, Muriel Charlotte Hans, Michelle Bous, Sybelle Goedicke-Fritz, Gudrun Wagenpfeil, Michael Zemlin, Erich-Franz Solomayer, Carolin Müller, Cosima Zemlin
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Breast Cancer Research
Subjects:
Breast cancer
T cells
Cytokines
Chemotherapy
Endocrine therapy
Biomarkers
Online Access:https://doi.org/10.1186/s13058-025-01997-9
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