The ionic and protonation states of flavin control the activation and recovery of Drosophila cryptochrome

Abstract Drosophila cryptochrome (dCry) is a flavin-containing photoreceptor. The release of C-terminal tail (CTT) upon illumination is a crucial step for the light sensing of dCry. Here, we demonstrated that both anionic semiquinone (asq) and anionic hydroquinone (hq) triggered CTT release, while n...

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Bibliographic Details
Main Authors: Wenlong Xie, Mengqi Wan, Yuting Dai, Yingjun Jiang, Mohan Wang, Lili Zhou, Li Zhang, Linmei Sun, Xiaoyu Feng, Tian Xia, Bin Wen, Jun Lv, Xiuxiu Wang, Lei Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01647-3
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