Bone Marrow Niche Aging: Are Adipocytes Detrimental Cells in the Bone Marrow?

Bone Marrow Niche Aging: Are Adipocytes Detrimental Cells in the Bone Marrow?

Aging disrupts the bone marrow (BM) niche, a complex microenvironment crucial for hematopoietic stem cell (HSC) maintenance. A key, yet debated, hallmark of this aging process is the accumulation of bone marrow adipocytes (BMAds). This review explores the evolving role of BMAds in the aging BM, part...

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Bibliographic Details
Main Authors: Urban Švajger, Patrik Milić, Primož J. Rožman
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
bone marrow niche
aging
adipocytes
Online Access:https://www.mdpi.com/2073-4409/14/11/814
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