Brown-Séquard, neurologist and father of endocrinology

Thomas Addison in 1855 described anaemia, general languor and debility, and a peculiar change of the colour in the skin in connexion with a diseased condition of the suprarenal capsules. But his famous monograph, did not mention a secretory role or vital humoral factor stemming from the adrenals....

Full description

Saved in:
Bibliographic Details
Main Author: John Pearce
Format: Article
Language:English
Published: Whitehouse Publishing 2025-07-01
Series:Advances in Clinical Neuroscience & Rehabilitation
Online Access:https://acnr.co.uk/articles/brown-sequard-neurologist-and-father-of-endocrinology/
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850113175100325888
author John Pearce
author_facet John Pearce
author_sort John Pearce
collection DOAJ
description Thomas Addison in 1855 described anaemia, general languor and debility, and a peculiar change of the colour in the skin in connexion with a diseased condition of the suprarenal capsules. But his famous monograph, did not mention a secretory role or vital humoral factor stemming from the adrenals. When the peripatetic experimental neurologist Brown-Séquard published (in1856) the results of his first experiments on the suprarenal glands it was not known that any of the vascular glands had a secretory function. He showed that animals dying from the absence in the blood of the secretion of those glands (after they had been removed) could be revived when they received an injection of a liquid extracted from healthy suprarenal capsules [glands]. Thus it was a neurologist Brown-Séquard who had established the essential secretory role of a glandular structure, the scientific foundation of endocrinology. Later, in 1902 Bayliss and Starling discovered secretin and introduced the word hormone.
format Article
id doaj-art-7190b5d5ae64447cb7e24d5d8b3369b1
institution OA Journals
issn 1473-9348
2397-267X
language English
publishDate 2025-07-01
publisher Whitehouse Publishing
record_format Article
series Advances in Clinical Neuroscience & Rehabilitation
spelling doaj-art-7190b5d5ae64447cb7e24d5d8b3369b12025-08-20T02:37:13ZengWhitehouse PublishingAdvances in Clinical Neuroscience & Rehabilitation1473-93482397-267X2025-07-0110.47795/FRMT6123Brown-Séquard, neurologist and father of endocrinologyJohn PearceThomas Addison in 1855 described anaemia, general languor and debility, and a peculiar change of the colour in the skin in connexion with a diseased condition of the suprarenal capsules. But his famous monograph, did not mention a secretory role or vital humoral factor stemming from the adrenals. When the peripatetic experimental neurologist Brown-Séquard published (in1856) the results of his first experiments on the suprarenal glands it was not known that any of the vascular glands had a secretory function. He showed that animals dying from the absence in the blood of the secretion of those glands (after they had been removed) could be revived when they received an injection of a liquid extracted from healthy suprarenal capsules [glands]. Thus it was a neurologist Brown-Séquard who had established the essential secretory role of a glandular structure, the scientific foundation of endocrinology. Later, in 1902 Bayliss and Starling discovered secretin and introduced the word hormone.https://acnr.co.uk/articles/brown-sequard-neurologist-and-father-of-endocrinology/
spellingShingle John Pearce
Brown-Séquard, neurologist and father of endocrinology
Advances in Clinical Neuroscience & Rehabilitation
title Brown-Séquard, neurologist and father of endocrinology
title_full Brown-Séquard, neurologist and father of endocrinology
title_fullStr Brown-Séquard, neurologist and father of endocrinology
title_full_unstemmed Brown-Séquard, neurologist and father of endocrinology
title_short Brown-Séquard, neurologist and father of endocrinology
title_sort brown sequard neurologist and father of endocrinology
url https://acnr.co.uk/articles/brown-sequard-neurologist-and-father-of-endocrinology/
work_keys_str_mv AT johnpearce brownsequardneurologistandfatherofendocrinology