Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2024-05-01
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| Series: | JACS Au |
| Online Access: | https://doi.org/10.1021/jacsau.4c00206 |
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| author | Isabella Ferrara Gleb A. Chesnokov Silvia Dittmann Olivier Blacque Susanne Sievers Karl Gademann |
| author_facet | Isabella Ferrara Gleb A. Chesnokov Silvia Dittmann Olivier Blacque Susanne Sievers Karl Gademann |
| author_sort | Isabella Ferrara |
| collection | DOAJ |
| format | Article |
| id | doaj-art-7189b696a8ff4065b19ca501db4f9a50 |
| institution | OA Journals |
| issn | 2691-3704 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | JACS Au |
| spelling | doaj-art-7189b696a8ff4065b19ca501db4f9a502025-08-20T02:01:16ZengAmerican Chemical SocietyJACS Au2691-37042024-05-01462267228010.1021/jacsau.4c00206Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic ActivityIsabella Ferrara0Gleb A. Chesnokov1Silvia Dittmann2Olivier Blacque3Susanne Sievers4Karl Gademann5Department of Chemistry, University of Zurich, Zürich, SwitzerlandDepartment of Chemistry, University of Zurich, Zürich, SwitzerlandDepartment for Microbial Physiology and Molecular Biology, Institute of Microbiology, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, GermanyDepartment of Chemistry, University of Zurich, Zürich, SwitzerlandDepartment for Microbial Physiology and Molecular Biology, Institute of Microbiology, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, GermanyDepartment of Chemistry, University of Zurich, Zürich, Switzerlandhttps://doi.org/10.1021/jacsau.4c00206 |
| spellingShingle | Isabella Ferrara Gleb A. Chesnokov Silvia Dittmann Olivier Blacque Susanne Sievers Karl Gademann Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity JACS Au |
| title | Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity |
| title_full | Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity |
| title_fullStr | Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity |
| title_full_unstemmed | Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity |
| title_short | Formal Single Atom Editing of the Glycosylated Natural Product Fidaxomicin Improves Acid Stability and Retains Antibiotic Activity |
| title_sort | formal single atom editing of the glycosylated natural product fidaxomicin improves acid stability and retains antibiotic activity |
| url | https://doi.org/10.1021/jacsau.4c00206 |
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