HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.

HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.

The increasing prevalence of acquired and transmitted HIV-1 drug resistance is an obstacle to successful antiretroviral therapy (ART) in the low- and middle-income countries (LMICs) hardest hit by the HIV-1 pandemic. Genotypic drug resistance testing could facilitate the choice of initial ART in are...

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Main Authors: Soo-Yon Rhee, Michael R Jordan, Elliot Raizes, Arlene Chua, Neil Parkin, Rami Kantor, Gert U Van Zyl, Irene Mukui, Mina C Hosseinipour, Lisa M Frenkel, Nicaise Ndembi, Raph L Hamers, Tobias F Rinke de Wit, Carole L Wallis, Ravindra K Gupta, Joseph Fokam, Clement Zeh, Jonathan M Schapiro, Sergio Carmona, David Katzenstein, Michele Tang, Avelin F Aghokeng, Tulio De Oliveira, Annemarie M J Wensing, Joel E Gallant, Mark A Wainberg, Douglas D Richman, Joseph E Fitzgibbon, Marco Schito, Silvia Bertagnolio, Chunfu Yang, Robert W Shafer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0145772
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