Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals
Summary: Background: While nosocomial influenza is common, the risk of transmission in acute care remains unclear in the absence of systematic surveillance. Even less is known about the risk of nosocomial respiratory syncytial virus (RSV) among immunocompetent adults. Aim: To compare the proportion...
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| Language: | English |
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Elsevier
2025-03-01
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| Series: | Infection Prevention in Practice |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590088924000957 |
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| author | Raija Auvinen Kaisa Huotari Hanna Nohynek Ritva K. Syrjänen Kirsi Skogberg |
| author_facet | Raija Auvinen Kaisa Huotari Hanna Nohynek Ritva K. Syrjänen Kirsi Skogberg |
| author_sort | Raija Auvinen |
| collection | DOAJ |
| description | Summary: Background: While nosocomial influenza is common, the risk of transmission in acute care remains unclear in the absence of systematic surveillance. Even less is known about the risk of nosocomial respiratory syncytial virus (RSV) among immunocompetent adults. Aim: To compare the proportions and incidences of nosocomial cases caused by these two similar respiratory infections among hospitalized adults. Methods: A retrospective study was conducted at two tertiary care hospitals in Southern Finland. Data on all hospitalized adult patients with a positive RSV or influenza test during 2016–22 were used to detect all nosocomial and community-acquired RSV and influenza cases. The proportion of nosocomial cases of all hospitalized cases was calculated. The incidences of nosocomial cases per 1000 bed-days were calculated by season and ward type for the five seasons before the COVID-19 pandemic. Results: Nosocomial RSV and influenza occurred in 2.8% and 8.1% of all hospitalized adult patients with a laboratory-confirmed infection. Over five seasons, 2016–20, the total incidences of nosocomial RSV and influenza cases per 1000 bed-days were 0.027 (95% confidence interval: 0.013, 0.050) and 0.32 (0.27, 0.39). Nosocomial RSV infections were especially poorly recorded with a virus-specific ICD-10 diagnosis code listed for only 16.7% of RSV and 59.8% of nosocomial influenza patients. Conclusion: Despite preventive measures, the incidence of nosocomial influenza was more than tenfold, and the proportion of nosocomial cases was almost threefold compared with RSV among hospitalized adults in acute care. Prevention and surveillance of both nosocomial influenza and RSV should be improved also among immunocompetent adult patients. |
| format | Article |
| id | doaj-art-718233bcce5c45cea9344af67a5f49c4 |
| institution | DOAJ |
| issn | 2590-0889 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Infection Prevention in Practice |
| spelling | doaj-art-718233bcce5c45cea9344af67a5f49c42025-08-20T03:00:50ZengElsevierInfection Prevention in Practice2590-08892025-03-017110043110.1016/j.infpip.2024.100431Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitalsRaija Auvinen0Kaisa Huotari1Hanna Nohynek2Ritva K. Syrjänen3Kirsi Skogberg4Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Department of Health Security, Finnish Institute for Health and Welfare, Helsinki, Finland; Corresponding author. Address: Jorvin sairaala, Infektioyksikkö, PL 800, 00029 HUS, Finland. Tel.: +358504271667.Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, FinlandDepartment of Health Security, Finnish Institute for Health and Welfare, Helsinki, FinlandFVR – Finnish Vaccine Research, Tampere, FinlandInflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, FinlandSummary: Background: While nosocomial influenza is common, the risk of transmission in acute care remains unclear in the absence of systematic surveillance. Even less is known about the risk of nosocomial respiratory syncytial virus (RSV) among immunocompetent adults. Aim: To compare the proportions and incidences of nosocomial cases caused by these two similar respiratory infections among hospitalized adults. Methods: A retrospective study was conducted at two tertiary care hospitals in Southern Finland. Data on all hospitalized adult patients with a positive RSV or influenza test during 2016–22 were used to detect all nosocomial and community-acquired RSV and influenza cases. The proportion of nosocomial cases of all hospitalized cases was calculated. The incidences of nosocomial cases per 1000 bed-days were calculated by season and ward type for the five seasons before the COVID-19 pandemic. Results: Nosocomial RSV and influenza occurred in 2.8% and 8.1% of all hospitalized adult patients with a laboratory-confirmed infection. Over five seasons, 2016–20, the total incidences of nosocomial RSV and influenza cases per 1000 bed-days were 0.027 (95% confidence interval: 0.013, 0.050) and 0.32 (0.27, 0.39). Nosocomial RSV infections were especially poorly recorded with a virus-specific ICD-10 diagnosis code listed for only 16.7% of RSV and 59.8% of nosocomial influenza patients. Conclusion: Despite preventive measures, the incidence of nosocomial influenza was more than tenfold, and the proportion of nosocomial cases was almost threefold compared with RSV among hospitalized adults in acute care. Prevention and surveillance of both nosocomial influenza and RSV should be improved also among immunocompetent adult patients.http://www.sciencedirect.com/science/article/pii/S2590088924000957Respiratory syncytial virusInfluenzaNosocomialAdultIncidence |
| spellingShingle | Raija Auvinen Kaisa Huotari Hanna Nohynek Ritva K. Syrjänen Kirsi Skogberg Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals Infection Prevention in Practice Respiratory syncytial virus Influenza Nosocomial Adult Incidence |
| title | Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| title_full | Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| title_fullStr | Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| title_full_unstemmed | Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| title_short | Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| title_sort | risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals |
| topic | Respiratory syncytial virus Influenza Nosocomial Adult Incidence |
| url | http://www.sciencedirect.com/science/article/pii/S2590088924000957 |
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