Development and characterization of a pseudovirus system for human Aichi virus: in vitro and in vivo analysis

Development and characterization of a pseudovirus system for human Aichi virus: in vitro and in vivo analysis

Abstract Human Aichi virus (AiV) (genus Kobuvirus, family Picornaviridae) has been described as a causative agent of human gastroenteritis since 1989. However, research on AiV at cellular and animal levels is limited. Utilizing a double reporter gene system, we constructed an AiV capsid protein plas...

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Bibliographic Details
Main Authors: Ruojun Wu, Jingli Tian, Shunchang Fan, Minyi Liang, Yucheng Li, Ying Deng, Binbin Tang, Minyi Zhang, Qing Chen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
Subjects:
Human Aichi virus
Pseudoviruses
Cells
Mouse model
Bioluminescent imaging
Online Access:https://doi.org/10.1186/s12985-025-02839-y
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