Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience
Mortality rate among maintenance hemodialysis (HD) patients with COVID-19 is alarmingly high. In Fatmawati General Hospital, most of HD patients with COVID-19 presented with acute respiratory distress syndrome (ARDS). Hemoperfusion (HP) is a blood purification therapy used to remove cytokines and in...
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Interna Publishing
2022-09-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2039 |
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| author | Elizabeth Yasmine Wardoyo Anggraini Permata Sari Aryan Y Djojo Johanes Sarwono Md Ikhsan Mokoagow Nikko Darnindro Jerry Nasarudin Marina Epriliawati Annela Manurung Martha Iskandar Krishna Adi Wibisana Anak Agung Arie Widyastuti Radhiyatam Mardiyah |
| author_facet | Elizabeth Yasmine Wardoyo Anggraini Permata Sari Aryan Y Djojo Johanes Sarwono Md Ikhsan Mokoagow Nikko Darnindro Jerry Nasarudin Marina Epriliawati Annela Manurung Martha Iskandar Krishna Adi Wibisana Anak Agung Arie Widyastuti Radhiyatam Mardiyah |
| author_sort | Elizabeth Yasmine Wardoyo |
| collection | DOAJ |
| description | Mortality rate among maintenance hemodialysis (HD) patients with COVID-19 is alarmingly high. In Fatmawati General Hospital, most of HD patients with COVID-19 presented with acute respiratory distress syndrome (ARDS). Hemoperfusion (HP) is a blood purification therapy used to remove cytokines and inflammatory mediators to prevent ARDS worsening and organ failure. We report 6 cases of COVID-19 in maintenance HD patients. HP and HD were performed in two consecutive days when patient developed early ARDS as indicated by inflammatory markers elevation. HP and HD were conducted by using resin-containing cartridge and high-flux dialyzer, respectively, for 4 hours. Improvements in CRP levels, PaO2/FiO2 ratios, and chest X-rays were observed after 2 sessions of HP in most of our patients. Based on our clinical experience, the timing of HP delivery is critical and should be undertaken in the early phase of ARDS, but larger studies are still needed. |
| format | Article |
| id | doaj-art-717c9b6fcc3f4f22b527c41e113908de |
| institution | OA Journals |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-717c9b6fcc3f4f22b527c41e113908de2025-08-20T02:37:12ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322022-09-01543Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre ExperienceElizabeth Yasmine Wardoyo0Anggraini Permata Sari1Aryan Y Djojo2Johanes Sarwono3Md Ikhsan Mokoagow4Nikko Darnindro5Jerry Nasarudin6Marina Epriliawati7Annela Manurung8Martha Iskandar9Krishna Adi Wibisana10Anak Agung Arie Widyastuti11Radhiyatam Mardiyah12Division of Renal Hypertension, Department of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDivision of Renal Hypertension, Department of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDivision of Renal Hypertension, Department of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDivision of Renal Hypertension, Department of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Fatmawati Hospital, Jakarta, IndonesiaMortality rate among maintenance hemodialysis (HD) patients with COVID-19 is alarmingly high. In Fatmawati General Hospital, most of HD patients with COVID-19 presented with acute respiratory distress syndrome (ARDS). Hemoperfusion (HP) is a blood purification therapy used to remove cytokines and inflammatory mediators to prevent ARDS worsening and organ failure. We report 6 cases of COVID-19 in maintenance HD patients. HP and HD were performed in two consecutive days when patient developed early ARDS as indicated by inflammatory markers elevation. HP and HD were conducted by using resin-containing cartridge and high-flux dialyzer, respectively, for 4 hours. Improvements in CRP levels, PaO2/FiO2 ratios, and chest X-rays were observed after 2 sessions of HP in most of our patients. Based on our clinical experience, the timing of HP delivery is critical and should be undertaken in the early phase of ARDS, but larger studies are still needed.http://www.actamedindones.org/index.php/ijim/article/view/2039hemoperfusionhemodialysisCOVID-19cytokinesresin |
| spellingShingle | Elizabeth Yasmine Wardoyo Anggraini Permata Sari Aryan Y Djojo Johanes Sarwono Md Ikhsan Mokoagow Nikko Darnindro Jerry Nasarudin Marina Epriliawati Annela Manurung Martha Iskandar Krishna Adi Wibisana Anak Agung Arie Widyastuti Radhiyatam Mardiyah Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience Acta Medica Indonesiana hemoperfusion hemodialysis COVID-19 cytokines resin |
| title | Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience |
| title_full | Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience |
| title_fullStr | Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience |
| title_full_unstemmed | Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience |
| title_short | Hemoperfusion as an Adjuvant Therapy in Maintenance Hemodialysis Patients with Severe COVID-19: A Single Centre Experience |
| title_sort | hemoperfusion as an adjuvant therapy in maintenance hemodialysis patients with severe covid 19 a single centre experience |
| topic | hemoperfusion hemodialysis COVID-19 cytokines resin |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2039 |
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