Risk factors for recurrence in patients with acute ischemic stroke

Objective To investigate the risk factors for recurrence in patients with acute ischemic stroke (AIS). Methods A total of 4 051 AIS patients reported to the Shandong Province Chronic Disease Monitoring Information Management System by Yanzhou People’s Hospital of Jining from January 2017 to December...

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Bibliographic Details
Main Author: BIAN Yanhe, ZHOU Rui, ZHANG Dongfeng
Format: Article
Language:zho
Published: Editorial Office of Journal of Precision Medicine 2025-08-01
Series:精准医学杂志
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Online Access:https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/1754471596423-1883710978.pdf
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Summary:Objective To investigate the risk factors for recurrence in patients with acute ischemic stroke (AIS). Methods A total of 4 051 AIS patients reported to the Shandong Province Chronic Disease Monitoring Information Management System by Yanzhou People’s Hospital of Jining from January 2017 to December 2020 were enrolled, and according to the number of episodes, they were divided into initial onset group (1 episode) and recurrence group (>1 episode at an interval of >28 days). The two groups were matched at a ratio of 1∶1 according to sex, age (with a difference of ≤±2 years), and onset time (the same month in the same year). General information and laboratory markers were collected and compared between the two groups, and the logistic regression model was used to investigate the risk factors for recurrence in AIS patients. Results A total of 814 patients were enrolled in this study, with 407 patients in each group. There were significant differences between the two groups in the history of hypertension, coronary heart disease, and diabetes mellitus and the levels of diastolic pressure, serum aspartate ami-notransferase, serum high-density lipoprotein cholesterol, serum glucose, blood sodium, and blood chlorine on admission (W=68 110-90 655,χ2=21.491-46.964,P<0.05). The multivariate logistic regression analysis showed that the history of hypertension, coronary heart disease, and diabetes mellitus, a high diastolic pressure, and a short plasma thrombin time on admission were risk factors for recurrence in AIS patients (P<0.05). Conclusion The history of hypertension, coronary heart disease, and diabetes mellitus, a high diastolic pressure, and a short plasma thrombin time on admission are risk factors for recurrence in AIS patients. Health management should be enhanced for the population with the above factors, in order to prevent disease recurrence and improve the quality of life of patients.
ISSN:2096-529X