STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes

STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes

Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) represent complex hematopoietic malignancies characterized by ineffective hematopoiesis and dysregulated myeloid differentiation. Recent research has underscored the critical role of aberrant STAT signaling pathways, particularly invol...

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Bibliographic Details
Main Authors: Zoe King, Sudhamsh Reddy Desai, David A. Frank, Aditi Shastri
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Acute myeloid leukemia
Myelodysplastic syndromes
Transcription factors
STAT proteins
Therapeutic strategies
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000168
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