Pitfalls in Early Bioprocess Development Using Shake Flask Cultivations

Pitfalls in Early Bioprocess Development Using Shake Flask Cultivations

ABSTRACT For about 100 years, the shake flask has been established for biotechnological cultivations as one of the most important cultivation systems in early process development. Its appeal lies in its simple handling and highly versatile application for a wide range of cell types—from bacteria to...

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Bibliographic Details
Main Authors: Gesa Brauneck, Dominik Engel, Luca Antonia Grebe, Maximilian Hoffmann, Philipp Georg Lichtenberg, Anne Neuß, Marcel Mann, Jorgen Barsett Magnus
Format: Article
Language:English
Published: Wiley-VCH 2025-01-01
Series:Engineering in Life Sciences
Subjects:
biochemical engineering
bioprocess development
cultivation system
online monitoring
shake flask
Online Access:https://doi.org/10.1002/elsc.70001
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