Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics

ABSTRACT Pangolins face critical threats from illegal trade and habitat loss, making their conservation a global priority. Despite their ecological and conservation significance, these elusive creatures remain poorly understood, particularly regarding their phylogeography and genetic diversity. This...

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Main Authors: Fiona Hogan, Faye Wedrowicz, Ambika Pd. Khatiwada, Janardan Dev Joshi, Sam Wasser, Wendy Wright
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Ecology and Evolution
Subjects:
Online Access:https://doi.org/10.1002/ece3.70982
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author Fiona Hogan
Faye Wedrowicz
Ambika Pd. Khatiwada
Janardan Dev Joshi
Sam Wasser
Wendy Wright
author_facet Fiona Hogan
Faye Wedrowicz
Ambika Pd. Khatiwada
Janardan Dev Joshi
Sam Wasser
Wendy Wright
author_sort Fiona Hogan
collection DOAJ
description ABSTRACT Pangolins face critical threats from illegal trade and habitat loss, making their conservation a global priority. Despite their ecological and conservation significance, these elusive creatures remain poorly understood, particularly regarding their phylogeography and genetic diversity. This study successfully isolated DNA from two types of pangolin scat samples (whole scat and swabs) and blood that had been stored frozen for up to 3 years. A mitochondrial cytochrome b (424 bp) sequence was reliably generated from both types of scat samples, irrespective of whether the scat appeared in ‘good’ or ‘poor’ condition at the time of collection, and from the blood samples. Sanger sequencing identified four novel cytochrome b haplotypes, with distinct variations observed across sampling regions in Nepal (central and east). A comparison with reference sequences from China, Taiwan and Thailand revealed that the Chinese pangolins in Nepal represent a genetically distinct variant, differing by 15–19 base pairs from these other populations. These findings underscore significant genetic differentiation of Chinese pangolins in Nepal, with implications for the species' conservation and management. The methods described in this study are robust and adaptable, offering a valuable framework for broader genetic studies of pangolin populations across Nepal. Such approaches could facilitate the genetic mapping of pangolin variations, aiding in the identification of significant populations, the evaluation of conservation interventions and forensic applications to combat illegal poaching. This work emphasises the critical role of genetics in understanding and protecting pangolins, offering insights that are vital for their long‐term conservation.
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spelling doaj-art-7152d0b570d34ce9972cfa15250cf4b42025-08-20T03:13:50ZengWileyEcology and Evolution2045-77582025-02-01152n/an/a10.1002/ece3.70982Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife ForensicsFiona Hogan0Faye Wedrowicz1Ambika Pd. Khatiwada2Janardan Dev Joshi3Sam Wasser4Wendy Wright5Future Regions Research Centre Federation University Australia Victoria AustraliaFuture Regions Research Centre Federation University Australia Victoria AustraliaBiodiversity Research Institute (University of Oviedo, Principado of Asturias, Spanish National Research Council), Mieres Campus University of Oviedo Mieres Asturias SpainNational Trust for Nature Conservation Lalitpur NepalDepartment of Biology University of Washington Seattle Washington USAFuture Regions Research Centre Federation University Australia Victoria AustraliaABSTRACT Pangolins face critical threats from illegal trade and habitat loss, making their conservation a global priority. Despite their ecological and conservation significance, these elusive creatures remain poorly understood, particularly regarding their phylogeography and genetic diversity. This study successfully isolated DNA from two types of pangolin scat samples (whole scat and swabs) and blood that had been stored frozen for up to 3 years. A mitochondrial cytochrome b (424 bp) sequence was reliably generated from both types of scat samples, irrespective of whether the scat appeared in ‘good’ or ‘poor’ condition at the time of collection, and from the blood samples. Sanger sequencing identified four novel cytochrome b haplotypes, with distinct variations observed across sampling regions in Nepal (central and east). A comparison with reference sequences from China, Taiwan and Thailand revealed that the Chinese pangolins in Nepal represent a genetically distinct variant, differing by 15–19 base pairs from these other populations. These findings underscore significant genetic differentiation of Chinese pangolins in Nepal, with implications for the species' conservation and management. The methods described in this study are robust and adaptable, offering a valuable framework for broader genetic studies of pangolin populations across Nepal. Such approaches could facilitate the genetic mapping of pangolin variations, aiding in the identification of significant populations, the evaluation of conservation interventions and forensic applications to combat illegal poaching. This work emphasises the critical role of genetics in understanding and protecting pangolins, offering insights that are vital for their long‐term conservation.https://doi.org/10.1002/ece3.70982mitochondrial DNAnon‐invasive genetic samplingpangolinscat
spellingShingle Fiona Hogan
Faye Wedrowicz
Ambika Pd. Khatiwada
Janardan Dev Joshi
Sam Wasser
Wendy Wright
Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
Ecology and Evolution
mitochondrial DNA
non‐invasive genetic sampling
pangolin
scat
title Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
title_full Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
title_fullStr Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
title_full_unstemmed Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
title_short Genetic Evidence Reveals Distinct Lineage of Chinese Pangolin in Nepal: Insights From Scat and Blood Samples for Conservation and Wildlife Forensics
title_sort genetic evidence reveals distinct lineage of chinese pangolin in nepal insights from scat and blood samples for conservation and wildlife forensics
topic mitochondrial DNA
non‐invasive genetic sampling
pangolin
scat
url https://doi.org/10.1002/ece3.70982
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