Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years
Background: Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | IBRO Neuroscience Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667242125000193 |
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| author | Lei Gao Yazhou Wen Kunlin Guo Renqi Li Mao Mao Shanwu Feng Xian Wang |
| author_facet | Lei Gao Yazhou Wen Kunlin Guo Renqi Li Mao Mao Shanwu Feng Xian Wang |
| author_sort | Lei Gao |
| collection | DOAJ |
| description | Background: Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related or obesity-induced pain, aiming to analyze the current trends and hot spots as well as explore the underlying mechanisms. Methods: We searched reviews and articles on obesity-related or obesity-induced pain from 2005 to 2024 via the Web of Science Core Collection (WoSCC) database. We subsequently conducted bibliometric analysis employing WPS Office, a web-based bibliometric analysis platform (https://bibliometric.com), VOSviewer, Pajek, and CiteSpace. Results: In total, 347 papers were identified for bibliometric analysis. The country, institution, and journal with the greatest influence were the USA, Albert Einstein College of Medicine, and Headache, respectively. Dr. Lipton RB and Dr. Karppinen J were the top 2 influential authors on the basis of their significant number of publications and citations. The keywords for the latest burst were ''inflammation,'' ''risk,'' ''neuropathic pain,'' ''gene-related peptide,'' ''knee osteoarthritis,'' and ''validation.'' Notably, the article titled ''The association between chronic obesity and pain'' by Okifuji A received the highest number of citations as well as the strongest citation burst. He and colleagues noted a significant correlation between obesity and pain in terms of clinical manifestations, but this connection is indirect and is modulated by certain biomechanical and structural alterations linked to obesity, inflammatory agents, mood disorders, sleep disturbances, and lifestyles. Conclusion: There has been a notable surge in the number of articles published in the last two decades. The investigation into neuroendocrine and neuroimmune mechanisms underlying obesity-related or obesity-induced pain is expected to be a hot spot in the coming years. A potential strategy for treating chronic obesity and pain should pay attention to particular endocrine regulators, inflammatory cytokines, or immune cells that serve as central elements or crucial signaling pathways within this regulatory system. |
| format | Article |
| id | doaj-art-7152c50ba2a74477b6572caad8d67217 |
| institution | Kabale University |
| issn | 2667-2421 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IBRO Neuroscience Reports |
| spelling | doaj-art-7152c50ba2a74477b6572caad8d672172025-08-20T03:45:28ZengElsevierIBRO Neuroscience Reports2667-24212025-06-011831132210.1016/j.ibneur.2025.02.001Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 yearsLei Gao0Yazhou Wen1Kunlin Guo2Renqi Li3Mao Mao4Shanwu Feng5Xian Wang6Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaDepartment of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaDepartment of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaDepartment of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaDepartment of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaCorrespondence to: Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, No 123 Mochou Road, Tianfei Xiang, Nanjing, Jiangsu, China.; Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaCorrespondence to: Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, No 123 Mochou Road, Tianfei Xiang, Nanjing, Jiangsu, China.; Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, Jiangsu, ChinaBackground: Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related or obesity-induced pain, aiming to analyze the current trends and hot spots as well as explore the underlying mechanisms. Methods: We searched reviews and articles on obesity-related or obesity-induced pain from 2005 to 2024 via the Web of Science Core Collection (WoSCC) database. We subsequently conducted bibliometric analysis employing WPS Office, a web-based bibliometric analysis platform (https://bibliometric.com), VOSviewer, Pajek, and CiteSpace. Results: In total, 347 papers were identified for bibliometric analysis. The country, institution, and journal with the greatest influence were the USA, Albert Einstein College of Medicine, and Headache, respectively. Dr. Lipton RB and Dr. Karppinen J were the top 2 influential authors on the basis of their significant number of publications and citations. The keywords for the latest burst were ''inflammation,'' ''risk,'' ''neuropathic pain,'' ''gene-related peptide,'' ''knee osteoarthritis,'' and ''validation.'' Notably, the article titled ''The association between chronic obesity and pain'' by Okifuji A received the highest number of citations as well as the strongest citation burst. He and colleagues noted a significant correlation between obesity and pain in terms of clinical manifestations, but this connection is indirect and is modulated by certain biomechanical and structural alterations linked to obesity, inflammatory agents, mood disorders, sleep disturbances, and lifestyles. Conclusion: There has been a notable surge in the number of articles published in the last two decades. The investigation into neuroendocrine and neuroimmune mechanisms underlying obesity-related or obesity-induced pain is expected to be a hot spot in the coming years. A potential strategy for treating chronic obesity and pain should pay attention to particular endocrine regulators, inflammatory cytokines, or immune cells that serve as central elements or crucial signaling pathways within this regulatory system.http://www.sciencedirect.com/science/article/pii/S2667242125000193ObesityPainBibliometric analysisResearch trendsVOSviewerCiteSpace |
| spellingShingle | Lei Gao Yazhou Wen Kunlin Guo Renqi Li Mao Mao Shanwu Feng Xian Wang Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years IBRO Neuroscience Reports Obesity Pain Bibliometric analysis Research trends VOSviewer CiteSpace |
| title | Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years |
| title_full | Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years |
| title_fullStr | Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years |
| title_full_unstemmed | Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years |
| title_short | Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years |
| title_sort | research trends and hot spots in obesity induced pain a bibliometric analysis of the last 20 years |
| topic | Obesity Pain Bibliometric analysis Research trends VOSviewer CiteSpace |
| url | http://www.sciencedirect.com/science/article/pii/S2667242125000193 |
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