Comprehensive insights of Sneddon syndrome: A clinical perspective

BACKGROUND Sneddon’s syndrome is a rare thrombotic vasculopathy characterized by the coexistence of both cerebrovascular events and livedo reticularis. OBJECTIVE This review aims to raise awareness among physicians by discussing the whole clinical spectrum of the disease. Typically, Sneddon syndrome...

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Main Author: Ahmad Yousef Alazzam
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.1177/11795735241308767
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author Ahmad Yousef Alazzam
author_facet Ahmad Yousef Alazzam
author_sort Ahmad Yousef Alazzam
collection DOAJ
description BACKGROUND Sneddon’s syndrome is a rare thrombotic vasculopathy characterized by the coexistence of both cerebrovascular events and livedo reticularis. OBJECTIVE This review aims to raise awareness among physicians by discussing the whole clinical spectrum of the disease. Typically, Sneddon syndrome presents in middle-aged women with a cerebrovascular accident and a preexisting skin rash, which is livedo reticularis. Diagnosis is primarily clinical, relying on a high index of suspicion. Management focuses mainly on reducing the risk of cerebral infarctions and alleviating symptoms. CONCLUSION Further research is necessary to better understand the disease’s nature, which will contribute to improving early diagnosis and optimal management.
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spelling doaj-art-714f249a44a3491fa6df1112f7ca36362025-08-20T02:34:39ZengSAGE PublishingJournal of Central Nervous System Disease1179-57352024-12-011610.1177/11795735241308767Comprehensive insights of Sneddon syndrome: A clinical perspectiveAhmad Yousef AlazzamBACKGROUND Sneddon’s syndrome is a rare thrombotic vasculopathy characterized by the coexistence of both cerebrovascular events and livedo reticularis. OBJECTIVE This review aims to raise awareness among physicians by discussing the whole clinical spectrum of the disease. Typically, Sneddon syndrome presents in middle-aged women with a cerebrovascular accident and a preexisting skin rash, which is livedo reticularis. Diagnosis is primarily clinical, relying on a high index of suspicion. Management focuses mainly on reducing the risk of cerebral infarctions and alleviating symptoms. CONCLUSION Further research is necessary to better understand the disease’s nature, which will contribute to improving early diagnosis and optimal management.https://doi.org/10.1177/11795735241308767
spellingShingle Ahmad Yousef Alazzam
Comprehensive insights of Sneddon syndrome: A clinical perspective
Journal of Central Nervous System Disease
title Comprehensive insights of Sneddon syndrome: A clinical perspective
title_full Comprehensive insights of Sneddon syndrome: A clinical perspective
title_fullStr Comprehensive insights of Sneddon syndrome: A clinical perspective
title_full_unstemmed Comprehensive insights of Sneddon syndrome: A clinical perspective
title_short Comprehensive insights of Sneddon syndrome: A clinical perspective
title_sort comprehensive insights of sneddon syndrome a clinical perspective
url https://doi.org/10.1177/11795735241308767
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