An organoid library of human esophageal squamous cell carcinomas (ESCCs) uncovers the chemotherapy-resistant ESCC features
Abstract Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with a poor prognosis and a high recurrence rate after chemotherapy, posing a significant clinical challenge. To elucidate the molecular basis of chemotherapy (chemo)-resistance and to develop methods to effectively eliminate chem...
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| Main Authors: | Shunsaku Nakagawa, Taku Sato, Eriko Ohashi, Mihoko Kajita, Fuyuki Miya, Kouhei Yamamoto, Hiroki Yotsumata, Kazuya Yamaguchi, Yasuaki Nakajima, Akinori Miura, Yusuke Kinugasa, Toshiaki Ohteki |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07869-4 |
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