Anion exchange chromatography-based purification of plant-derived nanovesicles from Brassica oleracea L.: molecular profiling and bioactivity in human cells

Anion exchange chromatography-based purification of plant-derived nanovesicles from Brassica oleracea L.: molecular profiling and bioactivity in human cells

Plant-derived nanovesicles emerge as a promising alternative to mammalian-derived exosomes with distinct advantages, including lower immunogenicity, enhanced bioavailability, and the presence of bioactive plant metabolites. They have been shown to cross biological barriers, delivering therapeutic mo...

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Main Authors: Clarissa Zanotti, Simona Arena, Sabrina De Pascale, Valentina Ciaravolo, Rosalia Ferracane, Antonio Dario Troise, Chiara Pontecorvi, Francesca Pacello, Chiara Niespolo, Angelo Gismondi, Andrea Scaloni, Mauro Marra
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
plant-derived nanovesicles
Brassica oleracea L.
proteomics
lipidomics
miRNomics
wound healing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1617478/full
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