A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery

Acute motor and sensory axonal neuropathy (AMSAN) is a rare axonal variant of Guillain-Barré syndrome. AMSAN is considered the most severe form of GBS, known for its rapid onset of severe symptoms, and often leading to quadriparesis within 7 days of initial symptom onset. We present a case of a midd...

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Main Authors: Jessica R. Dowling, Thomas J. Dowling
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2018/2384969
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author Jessica R. Dowling
Thomas J. Dowling
author_facet Jessica R. Dowling
Thomas J. Dowling
author_sort Jessica R. Dowling
collection DOAJ
description Acute motor and sensory axonal neuropathy (AMSAN) is a rare axonal variant of Guillain-Barré syndrome. AMSAN is considered the most severe form of GBS, known for its rapid onset of severe symptoms, and often leading to quadriparesis within 7 days of initial symptom onset. We present a case of a middle-aged Caucasian female who developed AMSAN 2 weeks following an elective spinal surgery. Although rare, GBS has been reported as a complication of surgery. GBS classically presents as ascending motor weakness starting in the lower extremities following a gastrointestinal or upper respiratory tract infection. This patient’s GBS manifested slightly differently, with both sensory and motor symptoms of her thoracic region and lower extremities, with no preceding history indicative of infection. To the authors’ knowledge, this is the first reported case of AMSAN following spinal surgery. Because of its risk of significant morbidity and mortality, as well as similar presentation to more common spinal postoperative complications, GBS should always be included in the differential diagnosis whenever motor or sensory weakness is observed after spinal surgery.
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spelling doaj-art-7121c084444c4adcb00d2d452c41fa5a2025-08-20T02:06:31ZengWileyCase Reports in Orthopedics2090-67492090-67572018-01-01201810.1155/2018/23849692384969A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal SurgeryJessica R. Dowling0Thomas J. Dowling1Charles E. Schmidt College of Medicine at Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USALong Island Spine Specialists PC, 763 Larkfield Road, Commack NY 11725, USAAcute motor and sensory axonal neuropathy (AMSAN) is a rare axonal variant of Guillain-Barré syndrome. AMSAN is considered the most severe form of GBS, known for its rapid onset of severe symptoms, and often leading to quadriparesis within 7 days of initial symptom onset. We present a case of a middle-aged Caucasian female who developed AMSAN 2 weeks following an elective spinal surgery. Although rare, GBS has been reported as a complication of surgery. GBS classically presents as ascending motor weakness starting in the lower extremities following a gastrointestinal or upper respiratory tract infection. This patient’s GBS manifested slightly differently, with both sensory and motor symptoms of her thoracic region and lower extremities, with no preceding history indicative of infection. To the authors’ knowledge, this is the first reported case of AMSAN following spinal surgery. Because of its risk of significant morbidity and mortality, as well as similar presentation to more common spinal postoperative complications, GBS should always be included in the differential diagnosis whenever motor or sensory weakness is observed after spinal surgery.http://dx.doi.org/10.1155/2018/2384969
spellingShingle Jessica R. Dowling
Thomas J. Dowling
A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
Case Reports in Orthopedics
title A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
title_full A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
title_fullStr A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
title_full_unstemmed A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
title_short A Rare Axonal Variant of Guillain-Barré Syndrome following Elective Spinal Surgery
title_sort rare axonal variant of guillain barre syndrome following elective spinal surgery
url http://dx.doi.org/10.1155/2018/2384969
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