Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma
We report a case of a sixty-three-year-old Chinese female with a known past history of primary, biopsy-diagnosed, ovarian high-grade serous carcinoma. Following three cycles of chemotherapy, she underwent total hysterectomy, bilateral salpingo-oophorectomy cytoreductive surgery with lymphadenectomy,...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2020/6468124 |
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| author | Jayanthi Karunanithi Inny Busmanis |
| author_facet | Jayanthi Karunanithi Inny Busmanis |
| author_sort | Jayanthi Karunanithi |
| collection | DOAJ |
| description | We report a case of a sixty-three-year-old Chinese female with a known past history of primary, biopsy-diagnosed, ovarian high-grade serous carcinoma. Following three cycles of chemotherapy, she underwent total hysterectomy, bilateral salpingo-oophorectomy cytoreductive surgery with lymphadenectomy, and multiple peritoneal biopsies. In this situation, the lymph nodes would be expected to demonstrate possible residual metastatic serous carcinoma with or without chemotherapy effect. The final diagnostic assessment in the lymph nodes, in this patient, however, was a rare combination of the following pathologies: metastatic serous carcinoma, with areas of chemotherapy effect, and incidental PEComatosis, focally in association with endometriosis, both within lymph nodes and surrounding connective tissue. PEComas have been described in patients with the tuberous sclerosis complex, but the current patient was not known to suffer from this condition. This case is also unusual, as although PEComas have been described as arising in the female genital tract, the associated phenomenon of endometriosis is exceedingly rare, and this is the first known reported case of lymph nodes harbouring a similar combination of pathologies. |
| format | Article |
| id | doaj-art-711390068312415db60637055cc53462 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-711390068312415db60637055cc534622025-02-03T06:46:00ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922020-01-01202010.1155/2020/64681246468124Surprise Lymph Node Histology in a Patient with Ovarian Serous CarcinomaJayanthi Karunanithi0Inny Busmanis1Department of Histopathology, Singapore General Hospital, SingaporeDepartment of Histopathology, Singapore General Hospital, SingaporeWe report a case of a sixty-three-year-old Chinese female with a known past history of primary, biopsy-diagnosed, ovarian high-grade serous carcinoma. Following three cycles of chemotherapy, she underwent total hysterectomy, bilateral salpingo-oophorectomy cytoreductive surgery with lymphadenectomy, and multiple peritoneal biopsies. In this situation, the lymph nodes would be expected to demonstrate possible residual metastatic serous carcinoma with or without chemotherapy effect. The final diagnostic assessment in the lymph nodes, in this patient, however, was a rare combination of the following pathologies: metastatic serous carcinoma, with areas of chemotherapy effect, and incidental PEComatosis, focally in association with endometriosis, both within lymph nodes and surrounding connective tissue. PEComas have been described in patients with the tuberous sclerosis complex, but the current patient was not known to suffer from this condition. This case is also unusual, as although PEComas have been described as arising in the female genital tract, the associated phenomenon of endometriosis is exceedingly rare, and this is the first known reported case of lymph nodes harbouring a similar combination of pathologies.http://dx.doi.org/10.1155/2020/6468124 |
| spellingShingle | Jayanthi Karunanithi Inny Busmanis Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma Case Reports in Obstetrics and Gynecology |
| title | Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma |
| title_full | Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma |
| title_fullStr | Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma |
| title_full_unstemmed | Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma |
| title_short | Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma |
| title_sort | surprise lymph node histology in a patient with ovarian serous carcinoma |
| url | http://dx.doi.org/10.1155/2020/6468124 |
| work_keys_str_mv | AT jayanthikarunanithi surpriselymphnodehistologyinapatientwithovarianserouscarcinoma AT innybusmanis surpriselymphnodehistologyinapatientwithovarianserouscarcinoma |