Study protocol for the Bio-HEAT study: Investigating the Biological pathways from HEAT exposure to preterm birth and other adverse maternal and child health outcomes in South Africa [version 2; peer review: 2 approved, 1 approved with reservations]

Study protocol for the Bio-HEAT study: Investigating the Biological pathways from HEAT exposure to preterm birth and other adverse maternal and child health outcomes in South Africa [version 2; peer review: 2 approved, 1 approved with reservations]

Introduction Epidemiological evidence linking heat exposure to adverse maternal and child health outcomes is compelling. However, the biological and social mechanisms underlying these associations remain poorly understood. Understanding the pathways explaining these associations is important given r...

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Main Authors: Lebohang Radebe, Nicholas B. Brink, Clive Gray, Marié Landsberg, Robyn Hetem, G Justus Hofmeyr, Phelelani T. Mpangase, Sibusisiwe Makhanya, Michael Urban, Shane Norris, Amy Wise, Valerie Vannevel, Karl-Gunter Technau, Matthew F. Chersich, Renate Strehlau, Ijeoma Solarin, Kimberly Mc Alpine, Darshnika Pemi Lakhoo, Admire Chikandiwa, Howard Chang, Margaret M. Brennan
Format: Article
Language:English
Published: Wellcome 2025-06-01
Series:Wellcome Open Research
Subjects:
Hot Temperature
Inflammation
Pregnancy
Premature birth
Maternal health
Breastfeeding
eng
Online Access:https://wellcomeopenresearch.org/articles/10-121/v2
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