The intrinsically disordered AB region: a key modulator of the molecular properties of human RXRγ

The intrinsically disordered AB region: a key modulator of the molecular properties of human RXRγ

Abstract The human retinoid X receptor γ (hRXRγ) is one of three characterized RXR subtypes, transcription factors belonging to the nuclear receptor superfamily. All RXR subtypes share nearly identical structural elements, including a conserved DNA-binding domain, a D region, a ligand-binding domain...

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Bibliographic Details
Main Authors: Katarzyna Sołtys, Krzysztof Skowronek, Dominika Bystranowska, Krzysztof Wycisk, Andrzej Ożyhar
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
Subjects:
Nuclear receptors
Retinoid X receptor
Oligomerization
9cRA
Stability
Intrinsically disordered regions
Online Access:https://doi.org/10.1186/s12964-025-02247-3
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