Immunotherapy resistance in non-small cell lung cancer: from mechanisms to therapeutic opportunities

Immunotherapy resistance in non-small cell lung cancer: from mechanisms to therapeutic opportunities

Abstract This review provides a comprehensive synthesis of current knowledge on immunotherapy resistance in non-small cell lung cancer (NSCLC), a disease that accounts for approximately 85% of all lung cancer cases and remains the leading cause of cancer-related death worldwide. Although immune chec...

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Bibliographic Details
Main Authors:	Huiyu Wang, Xiaomin Niu, Zhenning Jin, Shaoxing Zhang, Rong Fan, Hua Xiao, Shen S. Hu
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	Lung cancer Immunotherapy ICIs Immune resistance Combination therapy
Online Access:	https://doi.org/10.1186/s13046-025-03519-z
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