Explosive tumor growth in a patient with colon cancer is associated with reduced neoantigen levels and decreased interferon-gamma (IFN-γ) signaling

Abstract Background Explosive tumor growth is characterized by rapid tumor growth in a short time period. Currently, there is no precise scientific definition for the condition, which is often accompanied with a poor clinical prognosis. Herein, we presented a study of a young patient with colon canc...

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Bibliographic Details
Main Authors:	Yaqi Wang, Jiahua Lu, Dandan Huang, Pengju Chen, Jingyi Shi, Jie Cheng, Jingbo Gan, Ruifeng Li, Jingxuan Xu, Zhaoya Gao, Xiaodong Wang, Wensheng Huang, Yanhui Yin, Hebing Chen, Jing Huang, Cheng Li, Jin Gu
Format:	Article
Language:	English
Published:	BMC 2025-06-01
Series:	BMC Cancer
Subjects:	Colorectal cancer Explosive tumor growth Lynch syndrome Immunotherapy
Online Access:	https://doi.org/10.1186/s12885-025-14211-y
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Explosive tumor growth in a patient with colon cancer is associated with reduced neoantigen levels and decreased interferon-gamma (IFN-γ) signaling

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