Lymphomatoid granulomatosis with rare manifestations. Case report

Introduction: lymphomatoid granulomatosis is a very rare disease; This is the first case reported in the hospital. Patient information: 44-year-old male, with a health history and no toxic habits, who began with respiratory symptoms, dermatological lesions, constitutional syndrome and flaccid parapl...

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Main Authors: Pedro Rosales Torres, Pedro León Acosta
Format: Article
Language:Spanish
Published: Editorial Ciencias Médicas 2024-01-01
Series:Acta Médica del Centro
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Online Access:https://revactamedicacentro.sld.cu/index.php/amc/article/view/1912
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author Pedro Rosales Torres
Pedro León Acosta
author_facet Pedro Rosales Torres
Pedro León Acosta
author_sort Pedro Rosales Torres
collection DOAJ
description Introduction: lymphomatoid granulomatosis is a very rare disease; This is the first case reported in the hospital. Patient information: 44-year-old male, with a health history and no toxic habits, who began with respiratory symptoms, dermatological lesions, constitutional syndrome and flaccid paraplegia. Complementary examinations showed pancytopenia, and the chest x-ray and tomography showed an image suggestive of lung metastasis; An MRI showed a compressive lesion at the dorsal level. The anatomopathological studies of the skin and lung showed a lymphomatoid granulomatosis with medullary invasion. The patient was treated with chemotherapy and died abruptly one month after it began. Conclusions: lymphomatoid granulomatosis is a rare disease currently considered a lymphoid neoplasm associated with Epstein-Barr virus and large B cell lymphoma. It occurs in this patient accompanied by neurological injury; The diagnosis was only possible by anatomopathological studies. It was impossible to perform an autopsy due to family refusal.
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spelling doaj-art-70f9108117b24d62a74be9228f332eda2025-02-05T02:08:57ZspaEditorial Ciencias MédicasActa Médica del Centro2709-79272024-01-01181e1912e19121221Lymphomatoid granulomatosis with rare manifestations. Case reportPedro Rosales Torres0Pedro León Acosta1Hospital Provincial Clínico Quirúrgico Universitario “Manuel Ascunce Domenech”Hospital Provincial Clínico Quirúrgico Universitario “Manuel Ascunce Domenech”Introduction: lymphomatoid granulomatosis is a very rare disease; This is the first case reported in the hospital. Patient information: 44-year-old male, with a health history and no toxic habits, who began with respiratory symptoms, dermatological lesions, constitutional syndrome and flaccid paraplegia. Complementary examinations showed pancytopenia, and the chest x-ray and tomography showed an image suggestive of lung metastasis; An MRI showed a compressive lesion at the dorsal level. The anatomopathological studies of the skin and lung showed a lymphomatoid granulomatosis with medullary invasion. The patient was treated with chemotherapy and died abruptly one month after it began. Conclusions: lymphomatoid granulomatosis is a rare disease currently considered a lymphoid neoplasm associated with Epstein-Barr virus and large B cell lymphoma. It occurs in this patient accompanied by neurological injury; The diagnosis was only possible by anatomopathological studies. It was impossible to perform an autopsy due to family refusal.https://revactamedicacentro.sld.cu/index.php/amc/article/view/1912granulomatosis linfomatoidediagnósticotratamiento
spellingShingle Pedro Rosales Torres
Pedro León Acosta
Lymphomatoid granulomatosis with rare manifestations. Case report
Acta Médica del Centro
granulomatosis linfomatoide
diagnóstico
tratamiento
title Lymphomatoid granulomatosis with rare manifestations. Case report
title_full Lymphomatoid granulomatosis with rare manifestations. Case report
title_fullStr Lymphomatoid granulomatosis with rare manifestations. Case report
title_full_unstemmed Lymphomatoid granulomatosis with rare manifestations. Case report
title_short Lymphomatoid granulomatosis with rare manifestations. Case report
title_sort lymphomatoid granulomatosis with rare manifestations case report
topic granulomatosis linfomatoide
diagnóstico
tratamiento
url https://revactamedicacentro.sld.cu/index.php/amc/article/view/1912
work_keys_str_mv AT pedrorosalestorres lymphomatoidgranulomatosiswithraremanifestationscasereport
AT pedroleonacosta lymphomatoidgranulomatosiswithraremanifestationscasereport