Visual Outcome In Patients of Indirect Traumatic Optic Neuropathy Treated with Steroids

Aims: To assess the Visual Outcome in patients with Indirect TON Treated With Steroids. Settings and Design: Prospective Non Randomised Study. Methods and Material: 34 patients, having mild Traumatic Brain Injury (TBI) with unilateral indirect TON were included. All patients received treatment with...

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Bibliographic Details
Main Authors: Menezes Valerie, Usgaonkar Ugam, Menezes Ramona
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-04-01
Series:Delhi Journal of Ophthalmology
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Online Access:https://journals.lww.com/10.7869/djo.541
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Summary:Aims: To assess the Visual Outcome in patients with Indirect TON Treated With Steroids. Settings and Design: Prospective Non Randomised Study. Methods and Material: 34 patients, having mild Traumatic Brain Injury (TBI) with unilateral indirect TON were included. All patients received treatment with Methyl prednisolone 1 gm IV/day for 3 days followed by oral prednisolone 1 mg/kg for 11 days. Patients were divided into 2 groups. Group 1 included 17patients who received steroids within 72 hours of injury. Group 2 included 17 patients who received steroids after 72 hours of injury. Statistical analysis used: The Wilcoxon Signed Rank Test was used as the statistical test for visual acuity improvement for each of the groups. Fischerʼs exact test was used to assess statistical significance of visual acuity improvement between the 2 groups. Results: At 1 month follow up, 14 of 17 patients in Group 1 (82.4%) and 12 of 17 patients in Group 2 (70.6%) showed improvement in Visual Acuity which was statistically significant. The difference in visual acuity improvement between the two groups was not statistically significant. Conclusions: In patients of indirect TON having mild TBI, high dose steroids optimized the visual acuity, without any adverse effects, both in patients who presented within 72 hours and beyond 72 hours of injury.
ISSN:0972-0200
2454-2784