Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity

Purpose: To investigate the changes in posterior corneal elevation after small incision lenticule extraction (SMILE) surgery in eyes of different myopia severity. Methods: A total of 141 eyes of 86 patients were recruited and followed at 1 month, 3 months, 6 months, and 12 months after SMILE surgery...

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Main Authors: Li Jiang, Changting Tang, Bao Shu, Ying Liu, Qingyan Zeng, Xiaohua Lei, Zhengwei Shen, Yijun Hu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Photodiagnosis and Photodynamic Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S1572100024004290
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author Li Jiang
Changting Tang
Bao Shu
Ying Liu
Qingyan Zeng
Xiaohua Lei
Zhengwei Shen
Yijun Hu
author_facet Li Jiang
Changting Tang
Bao Shu
Ying Liu
Qingyan Zeng
Xiaohua Lei
Zhengwei Shen
Yijun Hu
author_sort Li Jiang
collection DOAJ
description Purpose: To investigate the changes in posterior corneal elevation after small incision lenticule extraction (SMILE) surgery in eyes of different myopia severity. Methods: A total of 141 eyes of 86 patients were recruited and followed at 1 month, 3 months, 6 months, and 12 months after SMILE surgery. The eyes were divided into four groups according to the spherical equivalent (SE): low myopia (LM, −3.00 D≤SE<−0.50 D, 35 eyes), moderate myopia (MM, −6.00 D≤SE<−3.00 D, 54 eyes) and high myopia (HM, −10.00 D≤SE<−6.00 D, 52 eyes). Posterior corneal elevation was measured by Pentacam HR. Posterior corneal apex elevation (PCAE), posterior maximum elevation (PME), and posterior elevation at the thinnest point of the cornea (TPC) in the central 4-mm area were recorded and compared among different examination time points in the same group or among different groups at the same time point. Results: Uncorrected distance visual acuity (UDVA) at 12 months was 20/20 or better in 100.00 % of eyes in LM group, 100.00 % in MM group and 96.15 % in HM group (P > 0.05). There were significant reductions of post-operative PCAE compared to baseline in the LM group (P = 0.038) and HM group (P<0.001), and the reduction was marginally significant in the MM group (P = 0.076). No statistically significant changes in PME were observed after SMILE surgery in the three groups (all P > 0.05). TPC was significantly decreased after the surgery in the MM group (P = 0.022) and the HM group (P<0.001), and was marginally significantly decreased in the LM group (P = 0.063). There was no significant difference in PCAE and PME among the three groups at baseline or any postoperative timepoint (all P > 0.05). TPC was significantly different among the three groups at 3 months, 6 months and 12 months (all P < 0.05), but not at baseline (P = 0.066) or 1 month (P = 0.080). Conclusion: In the first year after SMILE surgery, PCAE was decreased in both LM and HM eyes, and TPC were decreased in MM and HM eyes, but PME was stable after the surgery.
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spelling doaj-art-70efd5457c6c47cfb4afba892f7e19862025-08-20T02:38:22ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-12-015010439210.1016/j.pdpdt.2024.104392Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severityLi Jiang0Changting Tang1Bao Shu2Ying Liu3Qingyan Zeng4Xiaohua Lei5Zhengwei Shen6Yijun Hu7Refractive Surgery Center, Hankou Aier Eye Hospital, Wuhan, ChinaAffliliated Hospital of Guilin Medical University, Guilin, ChinaRefractive Surgery Center, Hankou Aier Eye Hospital, Wuhan, ChinaWuhan Bright Eye Hospital, Wuhan, ChinaRefractive Surgery Center, Hankou Aier Eye Hospital, Wuhan, ChinaRefractive Surgery Center, Hankou Aier Eye Hospital, Wuhan, China; Corresponding authors.Hubei Bright Eye Hospital, Wuhan, China; Wuhan Bright Eye Hospital, Wuhan, China; Corresponding authors.Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China; Corresponding authors.Purpose: To investigate the changes in posterior corneal elevation after small incision lenticule extraction (SMILE) surgery in eyes of different myopia severity. Methods: A total of 141 eyes of 86 patients were recruited and followed at 1 month, 3 months, 6 months, and 12 months after SMILE surgery. The eyes were divided into four groups according to the spherical equivalent (SE): low myopia (LM, −3.00 D≤SE<−0.50 D, 35 eyes), moderate myopia (MM, −6.00 D≤SE<−3.00 D, 54 eyes) and high myopia (HM, −10.00 D≤SE<−6.00 D, 52 eyes). Posterior corneal elevation was measured by Pentacam HR. Posterior corneal apex elevation (PCAE), posterior maximum elevation (PME), and posterior elevation at the thinnest point of the cornea (TPC) in the central 4-mm area were recorded and compared among different examination time points in the same group or among different groups at the same time point. Results: Uncorrected distance visual acuity (UDVA) at 12 months was 20/20 or better in 100.00 % of eyes in LM group, 100.00 % in MM group and 96.15 % in HM group (P > 0.05). There were significant reductions of post-operative PCAE compared to baseline in the LM group (P = 0.038) and HM group (P<0.001), and the reduction was marginally significant in the MM group (P = 0.076). No statistically significant changes in PME were observed after SMILE surgery in the three groups (all P > 0.05). TPC was significantly decreased after the surgery in the MM group (P = 0.022) and the HM group (P<0.001), and was marginally significantly decreased in the LM group (P = 0.063). There was no significant difference in PCAE and PME among the three groups at baseline or any postoperative timepoint (all P > 0.05). TPC was significantly different among the three groups at 3 months, 6 months and 12 months (all P < 0.05), but not at baseline (P = 0.066) or 1 month (P = 0.080). Conclusion: In the first year after SMILE surgery, PCAE was decreased in both LM and HM eyes, and TPC were decreased in MM and HM eyes, but PME was stable after the surgery.http://www.sciencedirect.com/science/article/pii/S1572100024004290Posterior corneal elevationCorneal biometricsRefractive surgeryMyopia
spellingShingle Li Jiang
Changting Tang
Bao Shu
Ying Liu
Qingyan Zeng
Xiaohua Lei
Zhengwei Shen
Yijun Hu
Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
Photodiagnosis and Photodynamic Therapy
Posterior corneal elevation
Corneal biometrics
Refractive surgery
Myopia
title Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
title_full Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
title_fullStr Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
title_full_unstemmed Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
title_short Posterior corneal elevation after small incision lenticule extraction (SMILE) in eyes of different myopia severity
title_sort posterior corneal elevation after small incision lenticule extraction smile in eyes of different myopia severity
topic Posterior corneal elevation
Corneal biometrics
Refractive surgery
Myopia
url http://www.sciencedirect.com/science/article/pii/S1572100024004290
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