Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts

During the production of olive fruit and olive oil, considerable quantities of leaves remain as by-products, which are a rich source of biologically active substances, especially polyphenols, and can therefore be used as a raw material for their extraction. Various methods are used for this purpose....

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Main Authors: Mirna Mrkonjić Fuka, Slaven Jurić, Luka Han, Martina Grdiša, Marko Vinceković, Irina Tanuwidjaja
Format: Article
Language:Bulgarian
Published: University of Zagreb, Faculty of Agriculture 2024-12-01
Series:Journal of Central European Agriculture
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Online Access:https://jcea.agr.hr/articles/771447_Ekstrakcija_ukupnih_polifenola_iz_lista_masline_procjena_mikrobiolo_ke_isto_e_i_antimikrobne_aktivnosti_ekstrakata_hr.pdf
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author Mirna Mrkonjić Fuka
Slaven Jurić
Luka Han
Martina Grdiša
Marko Vinceković
Irina Tanuwidjaja
author_facet Mirna Mrkonjić Fuka
Slaven Jurić
Luka Han
Martina Grdiša
Marko Vinceković
Irina Tanuwidjaja
author_sort Mirna Mrkonjić Fuka
collection DOAJ
description During the production of olive fruit and olive oil, considerable quantities of leaves remain as by-products, which are a rich source of biologically active substances, especially polyphenols, and can therefore be used as a raw material for their extraction. Various methods are used for this purpose. One of them is ultrasound-assisted extraction (UAE), which has proven to be an effective and economically affordable method. The aim of this study was to compare the efficacy of ultrasound-assisted extraction (UAE) and conventional extraction (KE) in the extraction of total polyphenols from olive leaves using water as a solvent and to determine the antimicrobial activity of extracts as well as the microbiological purity of the olive leaves and the extracts obtained. In ultrasound-assisted extraction, the highest concentrations of polyphenolic compounds were extracted at an amplitude (A) of 100% in an extraction time of 6 min from 6 g leaf powder/L, and this method showed greater efficiency compared to the conventional extraction method. However, olive leaf extracts obtained showed no antimicrobial activity. Using a modified ultrasound-assisted extraction (MUAE) that includes lyophilization, an olive leaf extract with higher concentrations of total polyphenols was obtained, which showed an inhibitory effect on the bacteria Salmonella enterica subsp. enterica (DSM 14221), Escherichia coli (ATCC 25922) and Listeria innocua (ATCC 33090) at concentrations of 600 and 400 μg total polyphenols, while exhibiting an efficacy of up to 37.0% against conventional antibiotics in controlling infections caused by Gram-negative bacteria, i.e. up to 32.6% against antibiotics for controlling infections caused by Gram-positive bacteria. In addition, this study found that aerobic mesophilic and sporogenic bacteria, bacteria from the Enterobacteriaceae family and molds and yeasts make up the natural microbiota of the olive leaf. All extraction methods used had a bactericidal effect on species from the Enterobacteriaceae family and a fungicidal effect on molds and yeasts. However, aerobic mesophilic and sporogenic bacteria were found in all extracts, regardless of the extraction method used.
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publisher University of Zagreb, Faculty of Agriculture
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spelling doaj-art-70efd503d00e474eba148b0da6c6db002025-08-20T02:34:47ZbulUniversity of Zagreb, Faculty of AgricultureJournal of Central European Agriculture1332-90492024-12-012541107112010.5513/JCEA01/25.4.4360Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extractsMirna Mrkonjić FukaSlaven JurićLuka HanMartina GrdišaMarko VincekovićIrina TanuwidjajaDuring the production of olive fruit and olive oil, considerable quantities of leaves remain as by-products, which are a rich source of biologically active substances, especially polyphenols, and can therefore be used as a raw material for their extraction. Various methods are used for this purpose. One of them is ultrasound-assisted extraction (UAE), which has proven to be an effective and economically affordable method. The aim of this study was to compare the efficacy of ultrasound-assisted extraction (UAE) and conventional extraction (KE) in the extraction of total polyphenols from olive leaves using water as a solvent and to determine the antimicrobial activity of extracts as well as the microbiological purity of the olive leaves and the extracts obtained. In ultrasound-assisted extraction, the highest concentrations of polyphenolic compounds were extracted at an amplitude (A) of 100% in an extraction time of 6 min from 6 g leaf powder/L, and this method showed greater efficiency compared to the conventional extraction method. However, olive leaf extracts obtained showed no antimicrobial activity. Using a modified ultrasound-assisted extraction (MUAE) that includes lyophilization, an olive leaf extract with higher concentrations of total polyphenols was obtained, which showed an inhibitory effect on the bacteria Salmonella enterica subsp. enterica (DSM 14221), Escherichia coli (ATCC 25922) and Listeria innocua (ATCC 33090) at concentrations of 600 and 400 μg total polyphenols, while exhibiting an efficacy of up to 37.0% against conventional antibiotics in controlling infections caused by Gram-negative bacteria, i.e. up to 32.6% against antibiotics for controlling infections caused by Gram-positive bacteria. In addition, this study found that aerobic mesophilic and sporogenic bacteria, bacteria from the Enterobacteriaceae family and molds and yeasts make up the natural microbiota of the olive leaf. All extraction methods used had a bactericidal effect on species from the Enterobacteriaceae family and a fungicidal effect on molds and yeasts. However, aerobic mesophilic and sporogenic bacteria were found in all extracts, regardless of the extraction method used.https://jcea.agr.hr/articles/771447_Ekstrakcija_ukupnih_polifenola_iz_lista_masline_procjena_mikrobiolo_ke_isto_e_i_antimikrobne_aktivnosti_ekstrakata_hr.pdfolea europea l.ultrasound-assisted extractionpolyphenolspathogenic microbiotaantibiotics
spellingShingle Mirna Mrkonjić Fuka
Slaven Jurić
Luka Han
Martina Grdiša
Marko Vinceković
Irina Tanuwidjaja
Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
Journal of Central European Agriculture
olea europea l.
ultrasound-assisted extraction
polyphenols
pathogenic microbiota
antibiotics
title Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
title_full Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
title_fullStr Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
title_full_unstemmed Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
title_short Polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
title_sort polyphenol recovery from olive leaves and evaluation of the microbiological quality and antimicrobial potential of the extracts
topic olea europea l.
ultrasound-assisted extraction
polyphenols
pathogenic microbiota
antibiotics
url https://jcea.agr.hr/articles/771447_Ekstrakcija_ukupnih_polifenola_iz_lista_masline_procjena_mikrobiolo_ke_isto_e_i_antimikrobne_aktivnosti_ekstrakata_hr.pdf
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AT martinagrdisa polyphenolrecoveryfromoliveleavesandevaluationofthemicrobiologicalqualityandantimicrobialpotentialoftheextracts
AT markovincekovic polyphenolrecoveryfromoliveleavesandevaluationofthemicrobiologicalqualityandantimicrobialpotentialoftheextracts
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