Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines

Cysticercosis is a significant public health problem in countries where pigs are raised for consumption and remains an important cause of neurological disease worldwide. The Philippines is considered an endemic area for cysticercosis because cases in both humans and pigs have been reported; however,...

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Main Authors: Jin-Mei Xu, Luz P. Acosta, Min Hou, Daria L. Manalo, Mario Jiz, Blanca Jarilla, Archie O. Pablo, Remigio M. Ovleda, Gretchen Langdon, Stephen T. McGarvey, Jonathan D. Kurtis, Jennifer F. Friedman, Hai-Wei Wu
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2010/603174
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author Jin-Mei Xu
Luz P. Acosta
Min Hou
Daria L. Manalo
Mario Jiz
Blanca Jarilla
Archie O. Pablo
Remigio M. Ovleda
Gretchen Langdon
Stephen T. McGarvey
Jonathan D. Kurtis
Jennifer F. Friedman
Hai-Wei Wu
author_facet Jin-Mei Xu
Luz P. Acosta
Min Hou
Daria L. Manalo
Mario Jiz
Blanca Jarilla
Archie O. Pablo
Remigio M. Ovleda
Gretchen Langdon
Stephen T. McGarvey
Jonathan D. Kurtis
Jennifer F. Friedman
Hai-Wei Wu
author_sort Jin-Mei Xu
collection DOAJ
description Cysticercosis is a significant public health problem in countries where pigs are raised for consumption and remains an important cause of neurological disease worldwide. The Philippines is considered an endemic area for cysticercosis because cases in both humans and pigs have been reported; however, epidemiologic information stays limited. We conducted a pilot survey of the seroprevalence of human cysticercosis in a village in Leyte, the Philippines, by measuring antibody specific for Taenia solium cyst-fluid antigen. There were 497 subjects aged 7–30 years in our study and most subjects were infected with one or more helminths. The overall cysticercosis seroprevalence in this population was 24.6% (95% CI: 20.82% ~ 28.58%) with no significant difference based on age, sex, or other helminth coinfection status. Although the sample may not be representative of the whole community, the findings suggest that cysticercosis is a significant, but underrecognized public health concern in the Philippines.
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spelling doaj-art-70ea702dce034bc097804de55f6853352025-08-20T02:06:46ZengWileyJournal of Tropical Medicine1687-96861687-96942010-01-01201010.1155/2010/603174603174Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the PhilippinesJin-Mei Xu0Luz P. Acosta1Min Hou2Daria L. Manalo3Mario Jiz4Blanca Jarilla5Archie O. Pablo6Remigio M. Ovleda7Gretchen Langdon8Stephen T. McGarvey9Jonathan D. Kurtis10Jennifer F. Friedman11Hai-Wei Wu12Department of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu 210029, ChinaDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesDepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu 210029, ChinaDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesDepartment of Immunology, Research Institute for Tropical Medicine, Department of Health, Manila 1781, PhilippinesCenter for International Health Research, Rhode Island Hospital, Providence, RI 02906, USAInternational Health Institute, Brown University School of Medicine, Providence, RI 02912, USACenter for International Health Research, Rhode Island Hospital, Providence, RI 02906, USACenter for International Health Research, Rhode Island Hospital, Providence, RI 02906, USADepartment of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu 210029, ChinaCysticercosis is a significant public health problem in countries where pigs are raised for consumption and remains an important cause of neurological disease worldwide. The Philippines is considered an endemic area for cysticercosis because cases in both humans and pigs have been reported; however, epidemiologic information stays limited. We conducted a pilot survey of the seroprevalence of human cysticercosis in a village in Leyte, the Philippines, by measuring antibody specific for Taenia solium cyst-fluid antigen. There were 497 subjects aged 7–30 years in our study and most subjects were infected with one or more helminths. The overall cysticercosis seroprevalence in this population was 24.6% (95% CI: 20.82% ~ 28.58%) with no significant difference based on age, sex, or other helminth coinfection status. Although the sample may not be representative of the whole community, the findings suggest that cysticercosis is a significant, but underrecognized public health concern in the Philippines.http://dx.doi.org/10.1155/2010/603174
spellingShingle Jin-Mei Xu
Luz P. Acosta
Min Hou
Daria L. Manalo
Mario Jiz
Blanca Jarilla
Archie O. Pablo
Remigio M. Ovleda
Gretchen Langdon
Stephen T. McGarvey
Jonathan D. Kurtis
Jennifer F. Friedman
Hai-Wei Wu
Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
Journal of Tropical Medicine
title Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
title_full Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
title_fullStr Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
title_full_unstemmed Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
title_short Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines
title_sort seroprevalence of cysticercosis in children and young adults living in a helminth endemic community in leyte the philippines
url http://dx.doi.org/10.1155/2010/603174
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