Pain characteristics in patients with hip osteoarthritis
Purpose: Exacerbations of osteoarthritis (OA) pain significantly impair activities of daily living and walking, thereby reducing quality of life. Despite various treatments, persistent pain remains a challenge, particularly in patients with hip OA, where pain perception mechanisms extend beyond noci...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Journal of Joint Surgery and Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949705124000252 |
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| author | Toru Nishiwaki Hisatoshi Ishikura Tatsuya Yamamoto |
| author_facet | Toru Nishiwaki Hisatoshi Ishikura Tatsuya Yamamoto |
| author_sort | Toru Nishiwaki |
| collection | DOAJ |
| description | Purpose: Exacerbations of osteoarthritis (OA) pain significantly impair activities of daily living and walking, thereby reducing quality of life. Despite various treatments, persistent pain remains a challenge, particularly in patients with hip OA, where pain perception mechanisms extend beyond nociceptive pain. This study examined the pain characteristics in patients with hip OA, with an emphasis on neuropathic pain and central sensitization (CS). Methods: A total of 421 patients scheduled for unilateral total hip arthroplasty were analyzed using the painDETECT score and Central Sensitization Inventory to classify the pain types as nociceptive (Noc), CS, neuropathic (Neu), or neuropathic with CS (NeuCS). Results: The results indicated that 72.9% of patients experienced Noc pain, while 5.0% experienced combined NeuCS pain. The Neu and NeuCS groups exhibited significantly lower modified Harris Hip Score and EuroQol-5 Dimensions Questionnaire (EQ-5D) scores than the Noc group, indicating worse clinical outcomes and quality of life. Neu pain was more intense at rest, and when combined with CS it significantly diminished the quality of life. Conclusion: These findings highlight the need for mechanism-based pain treatment strategies, such as Neu pain and CS components, which independently and cumulatively affect clinical scores and quality of life. This study highlights the importance of early recognition and targeted treatment of these pain mechanisms in patients with hip OA. Future research should focus on evaluating therapeutic interventions for Neu pain and CS to optimize patient outcomes. |
| format | Article |
| id | doaj-art-70e00bc28e164687b936ea801c854cd2 |
| institution | OA Journals |
| issn | 2949-7051 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Joint Surgery and Research |
| spelling | doaj-art-70e00bc28e164687b936ea801c854cd22025-08-20T02:23:45ZengElsevierJournal of Joint Surgery and Research2949-70512024-12-012416817210.1016/j.jjoisr.2024.09.003Pain characteristics in patients with hip osteoarthritisToru Nishiwaki0Hisatoshi Ishikura1Tatsuya Yamamoto2Corresponding author. Department of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, 8-2 Otemachi Aoi-ku, Shizuoka-city, Shizuoka 420-0853 Japan.; Department of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, 8-2 Otemachi Aoi-ku, Shizuoka-city, Shizuoka 420-0853, JapanDepartment of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, 8-2 Otemachi Aoi-ku, Shizuoka-city, Shizuoka 420-0853, JapanDepartment of Orthopaedic Surgery, Japanese Red Cross Shizuoka Hospital, 8-2 Otemachi Aoi-ku, Shizuoka-city, Shizuoka 420-0853, JapanPurpose: Exacerbations of osteoarthritis (OA) pain significantly impair activities of daily living and walking, thereby reducing quality of life. Despite various treatments, persistent pain remains a challenge, particularly in patients with hip OA, where pain perception mechanisms extend beyond nociceptive pain. This study examined the pain characteristics in patients with hip OA, with an emphasis on neuropathic pain and central sensitization (CS). Methods: A total of 421 patients scheduled for unilateral total hip arthroplasty were analyzed using the painDETECT score and Central Sensitization Inventory to classify the pain types as nociceptive (Noc), CS, neuropathic (Neu), or neuropathic with CS (NeuCS). Results: The results indicated that 72.9% of patients experienced Noc pain, while 5.0% experienced combined NeuCS pain. The Neu and NeuCS groups exhibited significantly lower modified Harris Hip Score and EuroQol-5 Dimensions Questionnaire (EQ-5D) scores than the Noc group, indicating worse clinical outcomes and quality of life. Neu pain was more intense at rest, and when combined with CS it significantly diminished the quality of life. Conclusion: These findings highlight the need for mechanism-based pain treatment strategies, such as Neu pain and CS components, which independently and cumulatively affect clinical scores and quality of life. This study highlights the importance of early recognition and targeted treatment of these pain mechanisms in patients with hip OA. Future research should focus on evaluating therapeutic interventions for Neu pain and CS to optimize patient outcomes.http://www.sciencedirect.com/science/article/pii/S2949705124000252Osteoarthritis of the hipCentral sensitizationNeuropathic painNociceptive pain |
| spellingShingle | Toru Nishiwaki Hisatoshi Ishikura Tatsuya Yamamoto Pain characteristics in patients with hip osteoarthritis Journal of Joint Surgery and Research Osteoarthritis of the hip Central sensitization Neuropathic pain Nociceptive pain |
| title | Pain characteristics in patients with hip osteoarthritis |
| title_full | Pain characteristics in patients with hip osteoarthritis |
| title_fullStr | Pain characteristics in patients with hip osteoarthritis |
| title_full_unstemmed | Pain characteristics in patients with hip osteoarthritis |
| title_short | Pain characteristics in patients with hip osteoarthritis |
| title_sort | pain characteristics in patients with hip osteoarthritis |
| topic | Osteoarthritis of the hip Central sensitization Neuropathic pain Nociceptive pain |
| url | http://www.sciencedirect.com/science/article/pii/S2949705124000252 |
| work_keys_str_mv | AT torunishiwaki paincharacteristicsinpatientswithhiposteoarthritis AT hisatoshiishikura paincharacteristicsinpatientswithhiposteoarthritis AT tatsuyayamamoto paincharacteristicsinpatientswithhiposteoarthritis |