Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy
This study employed the green synthesis approach to produce Selenium nanoparticles (Se-NPs) using Valeriana officinalis (Valerian) root extract as a biological agent for reduction and stabilization. The phytochemicals present in the extract enabled the generation of stable Se-NPs without the use of...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Open Ceramics |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666539525000951 |
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| author | Fatemeh Nazarzadeh Saied Navabpour Zahra Sabouri Majid Darroudi |
| author_facet | Fatemeh Nazarzadeh Saied Navabpour Zahra Sabouri Majid Darroudi |
| author_sort | Fatemeh Nazarzadeh |
| collection | DOAJ |
| description | This study employed the green synthesis approach to produce Selenium nanoparticles (Se-NPs) using Valeriana officinalis (Valerian) root extract as a biological agent for reduction and stabilization. The phytochemicals present in the extract enabled the generation of stable Se-NPs without the use of toxic chemicals. The nanoparticles underwent extensive characterization using UV–Vis spectroscopy, XRD, FTIR, and TEM images, confirming their structural, morphological, and surface properties. The Se-NPs demonstrated photocatalytic performance, which was confirmed by the efficient photodegradation of Rhodamine B (RhB) dye (98 % after 150 min). Furthermore, biological assays revealed that the nanoparticles exhibited selective cytotoxicity toward cancer B16F0 cells. This dual functionality, photocatalytic degradation, and selective anticancer effect highlight the applicability of Se-NPs in environmental and biomedical fields. |
| format | Article |
| id | doaj-art-70d3a6b374b0405a8dfd0208e359d8f6 |
| institution | Kabale University |
| issn | 2666-5395 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Open Ceramics |
| spelling | doaj-art-70d3a6b374b0405a8dfd0208e359d8f62025-08-20T03:56:17ZengElsevierOpen Ceramics2666-53952025-09-012310082810.1016/j.oceram.2025.100828Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapyFatemeh Nazarzadeh0Saied Navabpour1Zahra Sabouri2Majid Darroudi3Department of Plant Breeding and Biotechnology, Faculty of Plant Production, Agriculture and Natural Resources University of Gorgan, Gorgan, IranDepartment of Plant Breeding and Biotechnology, Faculty of Plant Production, Agriculture and Natural Resources University of Gorgan, Gorgan, Iran; Corresponding authors.Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Student Research Committee, Mashhad University of Medical Sciences, Mashhad, IranNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Corresponding authors.This study employed the green synthesis approach to produce Selenium nanoparticles (Se-NPs) using Valeriana officinalis (Valerian) root extract as a biological agent for reduction and stabilization. The phytochemicals present in the extract enabled the generation of stable Se-NPs without the use of toxic chemicals. The nanoparticles underwent extensive characterization using UV–Vis spectroscopy, XRD, FTIR, and TEM images, confirming their structural, morphological, and surface properties. The Se-NPs demonstrated photocatalytic performance, which was confirmed by the efficient photodegradation of Rhodamine B (RhB) dye (98 % after 150 min). Furthermore, biological assays revealed that the nanoparticles exhibited selective cytotoxicity toward cancer B16F0 cells. This dual functionality, photocatalytic degradation, and selective anticancer effect highlight the applicability of Se-NPs in environmental and biomedical fields.http://www.sciencedirect.com/science/article/pii/S2666539525000951Valeriana officinalisSelenium nanoparticlesPhotocatalytic performanceCytotoxicity |
| spellingShingle | Fatemeh Nazarzadeh Saied Navabpour Zahra Sabouri Majid Darroudi Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy Open Ceramics Valeriana officinalis Selenium nanoparticles Photocatalytic performance Cytotoxicity |
| title | Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy |
| title_full | Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy |
| title_fullStr | Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy |
| title_full_unstemmed | Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy |
| title_short | Biogenic synthesis of selenium nanoparticles from Valeriana officinalis extract: A dual approach for environmental remediation and cancer therapy |
| title_sort | biogenic synthesis of selenium nanoparticles from valeriana officinalis extract a dual approach for environmental remediation and cancer therapy |
| topic | Valeriana officinalis Selenium nanoparticles Photocatalytic performance Cytotoxicity |
| url | http://www.sciencedirect.com/science/article/pii/S2666539525000951 |
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