Potential candidate genes influencing meat production phenotypic traits in sheep: a review
This review examines the genetic basis of meat production phenotypic traits in sheep, addressing the challenge of enhancing carcass and meat quality to meet global demand. The article identifies key potential genes associated with vertebral traits, body size, muscle development, and fat deposition a...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2025.1616533/full |
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| _version_ | 1850105391771287552 |
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| author | Ying Han Muhammad Faheem Akhtar Wenting Chen Xiaotong Liu Mingyue Zhao Limeng Shi Muhammad Zahoor Khan Changfa Wang |
| author_facet | Ying Han Muhammad Faheem Akhtar Wenting Chen Xiaotong Liu Mingyue Zhao Limeng Shi Muhammad Zahoor Khan Changfa Wang |
| author_sort | Ying Han |
| collection | DOAJ |
| description | This review examines the genetic basis of meat production phenotypic traits in sheep, addressing the challenge of enhancing carcass and meat quality to meet global demand. The article identifies key potential genes associated with vertebral traits, body size, muscle development, and fat deposition across diverse sheep breeds worldwide. Through comprehensive analysis of recent literature (2018–2025), the study synthesizes findings from genome-wide association studies, candidate gene approaches, and transcriptomic analyses. Specific potential genes like VRTN, NR6A1, MSTN, ADIPOQ, LCORL, MEF2B, FASN, FABP4, SCD, DGAT1, BMP and HOX family genes demonstrate significant associations with economically valuable traits. The potential genes influencing meat production phenotypic traits (intramuscular fat contents, growth, vertebral traits and body size traits) have been highlighted in this review. This comprehensive genetic marker catalog serves as a critical resource repository for implementing marker-assisted selection programs, providing breeders and researchers with validated genetic targets to accelerate breeding efficiency and enhance meat production in sheep worldwide. |
| format | Article |
| id | doaj-art-70d247fd8640429fb315d35bd482dad2 |
| institution | OA Journals |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-70d247fd8640429fb315d35bd482dad22025-08-20T02:39:05ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-07-011210.3389/fvets.2025.16165331616533Potential candidate genes influencing meat production phenotypic traits in sheep: a reviewYing HanMuhammad Faheem AkhtarWenting ChenXiaotong LiuMingyue ZhaoLimeng ShiMuhammad Zahoor KhanChangfa WangThis review examines the genetic basis of meat production phenotypic traits in sheep, addressing the challenge of enhancing carcass and meat quality to meet global demand. The article identifies key potential genes associated with vertebral traits, body size, muscle development, and fat deposition across diverse sheep breeds worldwide. Through comprehensive analysis of recent literature (2018–2025), the study synthesizes findings from genome-wide association studies, candidate gene approaches, and transcriptomic analyses. Specific potential genes like VRTN, NR6A1, MSTN, ADIPOQ, LCORL, MEF2B, FASN, FABP4, SCD, DGAT1, BMP and HOX family genes demonstrate significant associations with economically valuable traits. The potential genes influencing meat production phenotypic traits (intramuscular fat contents, growth, vertebral traits and body size traits) have been highlighted in this review. This comprehensive genetic marker catalog serves as a critical resource repository for implementing marker-assisted selection programs, providing breeders and researchers with validated genetic targets to accelerate breeding efficiency and enhance meat production in sheep worldwide.https://www.frontiersin.org/articles/10.3389/fvets.2025.1616533/fullmeat productioncarcass weightvertebral traitssmall ruminantsgenetic markers |
| spellingShingle | Ying Han Muhammad Faheem Akhtar Wenting Chen Xiaotong Liu Mingyue Zhao Limeng Shi Muhammad Zahoor Khan Changfa Wang Potential candidate genes influencing meat production phenotypic traits in sheep: a review Frontiers in Veterinary Science meat production carcass weight vertebral traits small ruminants genetic markers |
| title | Potential candidate genes influencing meat production phenotypic traits in sheep: a review |
| title_full | Potential candidate genes influencing meat production phenotypic traits in sheep: a review |
| title_fullStr | Potential candidate genes influencing meat production phenotypic traits in sheep: a review |
| title_full_unstemmed | Potential candidate genes influencing meat production phenotypic traits in sheep: a review |
| title_short | Potential candidate genes influencing meat production phenotypic traits in sheep: a review |
| title_sort | potential candidate genes influencing meat production phenotypic traits in sheep a review |
| topic | meat production carcass weight vertebral traits small ruminants genetic markers |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2025.1616533/full |
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