Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates
BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.
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Main Authors: | R Slinger, L Yan, F Chan, K Forward, G Cooper-Lesins, L Best, D Haldane, S Veldhuyzen van Zanten |
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Format: | Article |
Language: | English |
Published: |
Wiley
2009-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/2009/695349 |
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