Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates
BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2009/695349 |
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| _version_ | 1832554963217154048 |
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| author | R Slinger L Yan F Chan K Forward G Cooper-Lesins L Best D Haldane S Veldhuyzen van Zanten |
| author_facet | R Slinger L Yan F Chan K Forward G Cooper-Lesins L Best D Haldane S Veldhuyzen van Zanten |
| author_sort | R Slinger |
| collection | DOAJ |
| description | BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens. |
| format | Article |
| id | doaj-art-70bb8993cb504eecabda088fa3334421 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-70bb8993cb504eecabda088fa33344212025-02-03T05:49:57ZengWileyCanadian Journal of Gastroenterology0835-79002009-01-0123960961210.1155/2009/695349Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori IsolatesR Slinger0L Yan1F Chan2K Forward3G Cooper-Lesins4L Best5D Haldane6S Veldhuyzen van Zanten7Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, CanadaEpigenDx Inc, Worcester, Massachusetts, USAChildren’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, CanadaDalhousie University, Halifax, Nova Scotia, CanadaQueen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, CanadaQueen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, CanadaQueen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, CanadaUniversity of Alberta, Edmonton, Alberta, CanadaBACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.http://dx.doi.org/10.1155/2009/695349 |
| spellingShingle | R Slinger L Yan F Chan K Forward G Cooper-Lesins L Best D Haldane S Veldhuyzen van Zanten Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates Canadian Journal of Gastroenterology |
| title | Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates |
| title_full | Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates |
| title_fullStr | Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates |
| title_full_unstemmed | Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates |
| title_short | Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates |
| title_sort | pyrosequencing assay to rapidly detect clarithromycin resistance mutations in canadian helicobacter pylori isolates |
| url | http://dx.doi.org/10.1155/2009/695349 |
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