Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures

Surgical resection was the first effective treatment for breast cancer and remains the most important treatment modality for curative intent. Refinements in operative techniques along with the use of adjuvant radiotherapy and advanced chemotherapeutic agents have facilitated increasingly focused bre...

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Main Authors: Jack W. Rostas, Donna Lynn Dyess
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2012/516417
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author Jack W. Rostas
Donna Lynn Dyess
author_facet Jack W. Rostas
Donna Lynn Dyess
author_sort Jack W. Rostas
collection DOAJ
description Surgical resection was the first effective treatment for breast cancer and remains the most important treatment modality for curative intent. Refinements in operative techniques along with the use of adjuvant radiotherapy and advanced chemotherapeutic agents have facilitated increasingly focused breast cancer operations. Surgical management of breast cancer has shifted from extensive and highly morbid procedures, to the modern concept obtaining the best possible cosmetic result in tandem with the appropriate oncological resection. An ever-growing comprehension of breast cancer biology has led to substantial advances in molecular diagnosis and targeted therapies. An emerging frontier involves the breast cancer microenvironment, as a thorough understanding, while currently lacking, represents a critical opportunity for diagnosis and treatment. Collectively, these improvements will continue to push all therapeutic interventions, including operative, toward the goal of becoming more focused, targeted, and less morbid.
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series International Journal of Breast Cancer
spelling doaj-art-70b7a541e4fa469ebff3f29b8e9092182025-08-20T03:34:01ZengWileyInternational Journal of Breast Cancer2090-31702090-31892012-01-01201210.1155/2012/516417516417Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger CuresJack W. Rostas0Donna Lynn Dyess1Department of Surgery, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue Mobile, AL 36604, USADepartment of Surgery, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue Mobile, AL 36604, USASurgical resection was the first effective treatment for breast cancer and remains the most important treatment modality for curative intent. Refinements in operative techniques along with the use of adjuvant radiotherapy and advanced chemotherapeutic agents have facilitated increasingly focused breast cancer operations. Surgical management of breast cancer has shifted from extensive and highly morbid procedures, to the modern concept obtaining the best possible cosmetic result in tandem with the appropriate oncological resection. An ever-growing comprehension of breast cancer biology has led to substantial advances in molecular diagnosis and targeted therapies. An emerging frontier involves the breast cancer microenvironment, as a thorough understanding, while currently lacking, represents a critical opportunity for diagnosis and treatment. Collectively, these improvements will continue to push all therapeutic interventions, including operative, toward the goal of becoming more focused, targeted, and less morbid.http://dx.doi.org/10.1155/2012/516417
spellingShingle Jack W. Rostas
Donna Lynn Dyess
Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
International Journal of Breast Cancer
title Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
title_full Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
title_fullStr Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
title_full_unstemmed Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
title_short Current Operative Management of Breast Cancer: An Age of Smaller Resections and Bigger Cures
title_sort current operative management of breast cancer an age of smaller resections and bigger cures
url http://dx.doi.org/10.1155/2012/516417
work_keys_str_mv AT jackwrostas currentoperativemanagementofbreastcanceranageofsmallerresectionsandbiggercures
AT donnalynndyess currentoperativemanagementofbreastcanceranageofsmallerresectionsandbiggercures