Biliary Obstruction due to a Pancreatic Plasmacytoma
Obstructive jaundice, weight loss, and anorexia often raise a concern for pancreatic malignancy. Although pancreatic adenocarcinoma is the most common form of pancreatic cancer, not all pancreatic malignancies are exocrine in origin. With advancement in endoscopic ultrasound with fine needle aspirat...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/9017617 |
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| author | Min Ho Cho Rohan Mandaliya Jennifer Tran Wen Lee Mitesh Patel |
| author_facet | Min Ho Cho Rohan Mandaliya Jennifer Tran Wen Lee Mitesh Patel |
| author_sort | Min Ho Cho |
| collection | DOAJ |
| description | Obstructive jaundice, weight loss, and anorexia often raise a concern for pancreatic malignancy. Although pancreatic adenocarcinoma is the most common form of pancreatic cancer, not all pancreatic malignancies are exocrine in origin. With advancement in endoscopic ultrasound with fine needle aspiration, it has become easier to make correct diagnosis. Plasmacytoma of pancreas is a solitary tumor of plasma cells and it can also lead to the same clinical presentations. Immunohistochemistry is required to make the diagnosis of plasmacytoma. However, when there are other systemic manifestations, such as hypercalcemia, renal injury, and anemia, a diagnosis of multiple myeloma should be suspected and confirmed by cytology or biopsy. It is very important to differentiate plasmacytoma from multiple myeloma as the management for each is different. Herein, we describe a case of multiple myeloma presenting as a pancreatic plasmacytoma causing obstructive jaundice. |
| format | Article |
| id | doaj-art-70b304efcd774e0ba39f4706a76097e4 |
| institution | OA Journals |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-70b304efcd774e0ba39f4706a76097e42025-08-20T02:06:47ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362018-01-01201810.1155/2018/90176179017617Biliary Obstruction due to a Pancreatic PlasmacytomaMin Ho Cho0Rohan Mandaliya1Jennifer Tran2Wen Lee3Mitesh Patel4Department of Medicine, MedStar Washington Hospital Center, Washington, DC, USADivision of Gastroenterology and Hepatology, MedStar Georgetown University Hospital, Washington, DC, USADepartment of Medicine, MedStar Washington Hospital Center, Washington, DC, USADepartment of Pathology, MedStar Washington Hospital Center, Washington, DC, USADivision of Gastroenterology, MedStar Washington Hospital Center, Washington, DC, USAObstructive jaundice, weight loss, and anorexia often raise a concern for pancreatic malignancy. Although pancreatic adenocarcinoma is the most common form of pancreatic cancer, not all pancreatic malignancies are exocrine in origin. With advancement in endoscopic ultrasound with fine needle aspiration, it has become easier to make correct diagnosis. Plasmacytoma of pancreas is a solitary tumor of plasma cells and it can also lead to the same clinical presentations. Immunohistochemistry is required to make the diagnosis of plasmacytoma. However, when there are other systemic manifestations, such as hypercalcemia, renal injury, and anemia, a diagnosis of multiple myeloma should be suspected and confirmed by cytology or biopsy. It is very important to differentiate plasmacytoma from multiple myeloma as the management for each is different. Herein, we describe a case of multiple myeloma presenting as a pancreatic plasmacytoma causing obstructive jaundice.http://dx.doi.org/10.1155/2018/9017617 |
| spellingShingle | Min Ho Cho Rohan Mandaliya Jennifer Tran Wen Lee Mitesh Patel Biliary Obstruction due to a Pancreatic Plasmacytoma Case Reports in Gastrointestinal Medicine |
| title | Biliary Obstruction due to a Pancreatic Plasmacytoma |
| title_full | Biliary Obstruction due to a Pancreatic Plasmacytoma |
| title_fullStr | Biliary Obstruction due to a Pancreatic Plasmacytoma |
| title_full_unstemmed | Biliary Obstruction due to a Pancreatic Plasmacytoma |
| title_short | Biliary Obstruction due to a Pancreatic Plasmacytoma |
| title_sort | biliary obstruction due to a pancreatic plasmacytoma |
| url | http://dx.doi.org/10.1155/2018/9017617 |
| work_keys_str_mv | AT minhocho biliaryobstructionduetoapancreaticplasmacytoma AT rohanmandaliya biliaryobstructionduetoapancreaticplasmacytoma AT jennifertran biliaryobstructionduetoapancreaticplasmacytoma AT wenlee biliaryobstructionduetoapancreaticplasmacytoma AT miteshpatel biliaryobstructionduetoapancreaticplasmacytoma |