Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model
Objective: to study the effect of a pulsatile flow-generation (PFG) device on the basic hemodynamic parameters of the circulatory system using a mathematical model.Results. Modelling and simulation showed that the use of PFG significantly (76%) increases aortic pulse pressure. The proposed mathemati...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2022-01-01
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| Series: | Вестник трансплантологии и искусственных органов |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/1423 |
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| author | G. P. Itkin A. I. Syrbu A. P. Kyleshov A. S. Buchnev A. A. Drobyshev |
| author_facet | G. P. Itkin A. I. Syrbu A. P. Kyleshov A. S. Buchnev A. A. Drobyshev |
| author_sort | G. P. Itkin |
| collection | DOAJ |
| description | Objective: to study the effect of a pulsatile flow-generation (PFG) device on the basic hemodynamic parameters of the circulatory system using a mathematical model.Results. Modelling and simulation showed that the use of PFG significantly (76%) increases aortic pulse pressure. The proposed mathematical model adequately describes the dynamics of the circulatory system and metabolism (oxygen debt) on physical activity in normal conditions and heart failure, and the use of non-pulsatile and pulsatile circulatory-assist systems. The mathematical model also shows that the use of PFG device blocks the development of rarefaction in the left ventricular cavity associated with a mismatch of blood inflow and outflow in diastolic phase when there is need to increase systemic blood flow by increasing the rotary pump speed. |
| format | Article |
| id | doaj-art-70a6fbddd7b84a41be02ce7502eddd19 |
| institution | Kabale University |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2022-01-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-70a6fbddd7b84a41be02ce7502eddd192025-08-20T03:59:53ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912022-01-01234737810.15825/1995-1191-2021-4-73-781059Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical modelG. P. Itkin0A. I. Syrbu1A. P. Kyleshov2A. S. Buchnev3A. A. Drobyshev4Shumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and TechnologyMoscow Institute of Physics and TechnologyShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansObjective: to study the effect of a pulsatile flow-generation (PFG) device on the basic hemodynamic parameters of the circulatory system using a mathematical model.Results. Modelling and simulation showed that the use of PFG significantly (76%) increases aortic pulse pressure. The proposed mathematical model adequately describes the dynamics of the circulatory system and metabolism (oxygen debt) on physical activity in normal conditions and heart failure, and the use of non-pulsatile and pulsatile circulatory-assist systems. The mathematical model also shows that the use of PFG device blocks the development of rarefaction in the left ventricular cavity associated with a mismatch of blood inflow and outflow in diastolic phase when there is need to increase systemic blood flow by increasing the rotary pump speed.https://journal.transpl.ru/vtio/article/view/1423mathematical modelcirculatory systempulsatile rotary blood pumppulsatile flow generation |
| spellingShingle | G. P. Itkin A. I. Syrbu A. P. Kyleshov A. S. Buchnev A. A. Drobyshev Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model Вестник трансплантологии и искусственных органов mathematical model circulatory system pulsatile rotary blood pump pulsatile flow generation |
| title | Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model |
| title_full | Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model |
| title_fullStr | Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model |
| title_full_unstemmed | Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model |
| title_short | Evaluation of the efficiency of a new pulsatile flow‑generating circulatory-assist system in rotary blood pumps. Research on a mathematical model |
| title_sort | evaluation of the efficiency of a new pulsatile flow generating circulatory assist system in rotary blood pumps research on a mathematical model |
| topic | mathematical model circulatory system pulsatile rotary blood pump pulsatile flow generation |
| url | https://journal.transpl.ru/vtio/article/view/1423 |
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