The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

The RNA-dependent RNA polymerase VP1 of infectious pancreatic necrosis virus (IPNV) is a single polypeptide responsible for both viral RNA transcription and genome replication. Sequence analysis identifies IPNV VP1 as having an unusual active site topology. We have purified, crystallized and solved...

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Bibliographic Details
Main Authors: Stephen C Graham, L Peter Sarin, Mohammad W Bahar, Reg A Myers, David I Stuart, Dennis H Bamford, Jonathan M Grimes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002085&type=printable
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