Lenalidomide and its impact on exanthematous reactions: a case report
Lenalidomide is a drug used mainly in the treatment of Multiple Myeloma and Myelodysplastic Syndrome. Despite its therapeutic benefits, lenalidomide can cause several adverse effects, including exanthematous reactions that can appear unexpectedly and cause discomfort to the patient. These skin react...
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| Format: | Article |
| Language: | English |
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Sociedade Portuguesa de Dermatologia e Venereologia
2025-04-01
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| Series: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
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| Online Access: | https://www.portuguesejournalofdermatology.com/frame_eng.php?id=224 |
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| author | Cristiana Vieira-Maia José E. Ramos Ana C. Morgado |
| author_facet | Cristiana Vieira-Maia José E. Ramos Ana C. Morgado |
| author_sort | Cristiana Vieira-Maia |
| collection | DOAJ |
| description | Lenalidomide is a drug used mainly in the treatment of Multiple Myeloma and Myelodysplastic Syndrome. Despite its therapeutic benefits, lenalidomide can cause several adverse effects, including exanthematous reactions that can appear unexpectedly and cause discomfort to the patient. These skin reactions can be mild or severe and sometimes require the discontinuation of the lenalidomide treatment. In this case study, we will present the case of an 86-year-old man with a history of multiple myeloma who was on his fifth cycle of lenalidomide 10 mg and dexamethasone 20 mg, who was seen at the Health Center for constipation after two visits to the emergency department. During the consultation, the objective examination revealed a scattered maculopapular rash, probably secondary to lenalidomide. Timely assessment and guidance in these situations can be crucial to the patient’s prognosis. Anamnesis is one of the fundamental pillars of medical diagnosis.
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| format | Article |
| id | doaj-art-7091ec7028d34e0d93d833e4c8f6e185 |
| institution | Kabale University |
| issn | 2182-2395 2182-2409 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Sociedade Portuguesa de Dermatologia e Venereologia |
| record_format | Article |
| series | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| spelling | doaj-art-7091ec7028d34e0d93d833e4c8f6e1852025-08-20T03:30:41ZengSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia2182-23952182-24092025-04-01832Lenalidomide and its impact on exanthematous reactions: a case reportCristiana Vieira-Maia0José E. Ramos1Ana C. Morgado2General Family Medicine, USF Aquae Flaviae, ULS Trás - Os - Montes e Alto Douro, Chaves, PortugalGeneral Family Medicine, USF Aquae Flaviae, ULS Trás - Os - Montes e Alto Douro, Chaves, PortugalGeneral Family Medicine, USF Aquae Flaviae, ULS Trás - Os - Montes e Alto Douro, Chaves, PortugalLenalidomide is a drug used mainly in the treatment of Multiple Myeloma and Myelodysplastic Syndrome. Despite its therapeutic benefits, lenalidomide can cause several adverse effects, including exanthematous reactions that can appear unexpectedly and cause discomfort to the patient. These skin reactions can be mild or severe and sometimes require the discontinuation of the lenalidomide treatment. In this case study, we will present the case of an 86-year-old man with a history of multiple myeloma who was on his fifth cycle of lenalidomide 10 mg and dexamethasone 20 mg, who was seen at the Health Center for constipation after two visits to the emergency department. During the consultation, the objective examination revealed a scattered maculopapular rash, probably secondary to lenalidomide. Timely assessment and guidance in these situations can be crucial to the patient’s prognosis. Anamnesis is one of the fundamental pillars of medical diagnosis. https://www.portuguesejournalofdermatology.com/frame_eng.php?id=224Anamnesis. Adverse effects. Exanthema. Hypersensitivity. Late onset. Lenalidomide. |
| spellingShingle | Cristiana Vieira-Maia José E. Ramos Ana C. Morgado Lenalidomide and its impact on exanthematous reactions: a case report Revista da Sociedade Portuguesa de Dermatologia e Venereologia Anamnesis. Adverse effects. Exanthema. Hypersensitivity. Late onset. Lenalidomide. |
| title | Lenalidomide and its impact on exanthematous reactions: a case report |
| title_full | Lenalidomide and its impact on exanthematous reactions: a case report |
| title_fullStr | Lenalidomide and its impact on exanthematous reactions: a case report |
| title_full_unstemmed | Lenalidomide and its impact on exanthematous reactions: a case report |
| title_short | Lenalidomide and its impact on exanthematous reactions: a case report |
| title_sort | lenalidomide and its impact on exanthematous reactions a case report |
| topic | Anamnesis. Adverse effects. Exanthema. Hypersensitivity. Late onset. Lenalidomide. |
| url | https://www.portuguesejournalofdermatology.com/frame_eng.php?id=224 |
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