Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis

Background: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Therefore, this study aimed to retrospectively compare the outcomes of patients undergoing their first ICSI cycle, across four seasons in Aseer Region, Saudi Arabia. Methods: Thi...

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Main Authors: Fatimah A. Alzahrani, Zainab Al Hubil, Abdullrahman Mohammed Bawahab, Mamdoh Eskandar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_901_24
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author Fatimah A. Alzahrani
Zainab Al Hubil
Abdullrahman Mohammed Bawahab
Mamdoh Eskandar
author_facet Fatimah A. Alzahrani
Zainab Al Hubil
Abdullrahman Mohammed Bawahab
Mamdoh Eskandar
author_sort Fatimah A. Alzahrani
collection DOAJ
description Background: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Therefore, this study aimed to retrospectively compare the outcomes of patients undergoing their first ICSI cycle, across four seasons in Aseer Region, Saudi Arabia. Methods: This study included 2,194 women who underwent their first intracytoplasmic sperm injection cycle in a private center in Abha City, Saudi Arabia during the period between January 2017 and September 2021. Women were divided according to the day of oocyte retrieval into Spring (n = 515), Summer (n = 583), Autumn (n = 589), and Winter (n = 503). Basal and stimulation characteristics were compared among the four study groups. Results: The age of participants ranged from 25 to 42 years (Mean ± SD: 34.72 ± 11.5 years). Fertilization rates were least during autumn, but highest during spring. In addition, live birth rates were least during summer and highest during autumn. However, all differences according to seasons were not statistically significant. Conclusion: Seasonality doesn’t affect pregnancy outcomes. The highest live birth rate in the autumn, and the lowest in summer. ICSI outcomes are consistent regardless of season, suggesting no need to consider seasonality in planning or performing ICSI.
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issn 0976-4879
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publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
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series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-7077f7f097754e9481a6effb6afce27f2025-08-20T02:40:27ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3402S340410.4103/jpbs.jpbs_901_24Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive AnalysisFatimah A. AlzahraniZainab Al HubilAbdullrahman Mohammed BawahabMamdoh EskandarBackground: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Therefore, this study aimed to retrospectively compare the outcomes of patients undergoing their first ICSI cycle, across four seasons in Aseer Region, Saudi Arabia. Methods: This study included 2,194 women who underwent their first intracytoplasmic sperm injection cycle in a private center in Abha City, Saudi Arabia during the period between January 2017 and September 2021. Women were divided according to the day of oocyte retrieval into Spring (n = 515), Summer (n = 583), Autumn (n = 589), and Winter (n = 503). Basal and stimulation characteristics were compared among the four study groups. Results: The age of participants ranged from 25 to 42 years (Mean ± SD: 34.72 ± 11.5 years). Fertilization rates were least during autumn, but highest during spring. In addition, live birth rates were least during summer and highest during autumn. However, all differences according to seasons were not statistically significant. Conclusion: Seasonality doesn’t affect pregnancy outcomes. The highest live birth rate in the autumn, and the lowest in summer. ICSI outcomes are consistent regardless of season, suggesting no need to consider seasonality in planning or performing ICSI.https://journals.lww.com/10.4103/jpbs.jpbs_901_24fertilization/implantation/pregnancy ratesinfertilityintracytoplasmic sperm injectionpregnancy outcomeseasonality
spellingShingle Fatimah A. Alzahrani
Zainab Al Hubil
Abdullrahman Mohammed Bawahab
Mamdoh Eskandar
Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
Journal of Pharmacy and Bioallied Sciences
fertilization/implantation/pregnancy rates
infertility
intracytoplasmic sperm injection
pregnancy outcome
seasonality
title Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
title_full Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
title_fullStr Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
title_full_unstemmed Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
title_short Seasonality’s Impact on Patients Receiving Intracytoplasmic Sperm Injections: A Reproductive Analysis
title_sort seasonality s impact on patients receiving intracytoplasmic sperm injections a reproductive analysis
topic fertilization/implantation/pregnancy rates
infertility
intracytoplasmic sperm injection
pregnancy outcome
seasonality
url https://journals.lww.com/10.4103/jpbs.jpbs_901_24
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AT zainabalhubil seasonalitysimpactonpatientsreceivingintracytoplasmicsperminjectionsareproductiveanalysis
AT abdullrahmanmohammedbawahab seasonalitysimpactonpatientsreceivingintracytoplasmicsperminjectionsareproductiveanalysis
AT mamdoheskandar seasonalitysimpactonpatientsreceivingintracytoplasmicsperminjectionsareproductiveanalysis